DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_653103.1	Gene:	Sec14l2 / 67815	MGIID:	1915065	Length:	403	Species:	Mus musculus

Alignment Length:	289	Identity:	51/289 - (17%)
Similarity:	100/289 - (34%)	Gaps:	83/289 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANTLRTLDPKL-AALAKSECNEEQAQRAEIIATIKTWITKSPHLKAPTDEQLILAFLRRCRFSQ 64
            |:..:..|.||. .||||...|.:     :::.|:..           .|:..:|.:||...|..
Mouse     1 MSGRVGDLSPKQEEALAKFRENVQ-----DVLPTLPN-----------PDDYFLLRWLRARSFDL 49

  Fly    65 EETKRRFDNYYSLRSVFPEVLGSRQVDEALLTQLQRGIHVIPMRPVSPEGPRVIISQFRN----- 124
            ::::.....:...|.       .:.:|:           :|..:|  ||    :|.|:.:
Mouse    50 QKSEAMLRKHVEFRK-------QKDIDK-----------IISWQP--PE----VIQQYLSGGRCG 90

  Fly   125 ---------------IDPK----KSNPREAFKLIFIMLELLALECDNAA------ISGLIWVVDA 164
                           :|.|    .::.::..:......|||..||....      |..:..:.|.
Mouse    91 YDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLLQECIQQTTKLGKKIETITMIYDC 155

  Fly   165 RDVTMEQMMQ-----YDPFLLKKAFALVDQCIPLRFVEIHMINMRKEGQTIFNFVTKFLPSKLPF 224
            ..:.::.:.:     |..||     .:.::..|.....:.::...|.....:|.:..||......
Mouse   156 EGLGLKHLWKPAVEAYGEFL-----TMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRR 215

  Fly   225 KFVV--HKKSEDLYQHLPRDVMTIEYGGT 251
            |.:|  ....|.|.:|:..|.:.:|||||
Mouse   216 KIMVLGANWKEVLLKHISPDQLPVEYGGT 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	32/192 (17%)
Sec14l2	NP_653103.1	CRAL_TRIO_N	13..59	CDD:215024	11/61 (18%)
		SEC14	76..244	CDD:214706	31/178 (17%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810