DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and clvs2

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001020716.1	Gene:	clvs2 / 566769	ZFINID:	ZDB-GENE-041014-313	Length:	329	Species:	Danio rerio

Alignment Length:	267	Identity:	58/267 - (21%)
Similarity:	110/267 - (41%)	Gaps:	13/267 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LDPKLAALAKSECNEEQAQRAEIIATIKTWITKSPHLK-APTDEQLILAFLRRCRFSQEETKRRF 71
            |.|:....||.|..|......:.|..::..|...|.:. ..||:..||.|||..:|:..|..|..
Zfish     8 LSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLL 72

  Fly    72 DNYYSLR----SVFPEVLGSRQVDEALLTQLQRGIHVIPMRPVSPEGPRVIISQFRNIDPKKSNP 132
            ..|:..|    .:|..:   :..|..:...|:.|...: :..:...|.::::....|.|..:...
Zfish    73 AQYFEYRQQNLDMFKNL---KATDPGIKQALKDGFPGV-LSNLDRYGRKILVLFAANWDQSRYTF 133

  Fly   133 REAFKLIFIMLELLALECDNAAISGLIWVVDARDVTMEQMMQYDPFLLKKAFALVDQCIPLRFVE 197
            .:..:.|.:.||.: :|.....::|.:.::|..:.|.:|..:..|.:|:.|...:....|.||..
Zfish   134 VDILRAILLSLEAM-IEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGG 197

  Fly   198 IHMINMRKEGQTIFNFVTKFLPSKLPFKFVVHKKS-EDLYQHLPRDVMTIEYGGTNGYQAEAVDH 261
            ||.:|.......::..:..||..|...:..:|..: ..|:|.:..:::..|.||.  .....:..
Zfish   198 IHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLILPEILPSELGGM--LPPYDMGT 260

  Fly   262 WRQKLLD 268
            |.:.|||
Zfish   261 WARTLLD 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	30/156 (19%)
clvs2	NP_001020716.1	CRAL_TRIO_N	29..75	CDD:215024	13/45 (29%)
		SEC14	106..251	CDD:238099	27/146 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579374
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750