DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and sec14l8

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001093463.1	Gene:	sec14l8 / 558964	ZFINID:	ZDB-GENE-060526-180	Length:	395	Species:	Danio rerio

Alignment Length:	245	Identity:	48/245 - (19%)
Similarity:	90/245 - (36%)	Gaps:	31/245 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QRAEIIATIKTWITK-SPHLKAPTDEQLILAFLRRCRFSQEETKRRFDNYYSLRS--VFPEVLGS 87
            ::||.:|..:..:.. .|...:.:| ..:|.:||...|:.::::.....:...|.  ....:...
Zfish    11 KQAEALAQFREKVQDVLPQCPSQSD-HFLLRWLRARNFNLQKSEAMLRKHIEFRKHMKVDTITTE 74

  Fly    88 RQVDEALLTQLQRGI--HVIPMRPV-----SPEGPRVIISQFRNIDPKKSNPREAFKLIFIMLEL 145
            .||.|.:...|..|:  |.....||     .|..|:.::......|..||..|:.        |:
Zfish    75 WQVPEVIDKYLSGGMCGHDREGSPVWYDVIGPLDPKGLMHSASKQDLIKSKVRDC--------EI 131

  Fly   146 LALECDNAA------ISGLIWVVDARDVTMEQMMQYDPFL--LKKAFALVDQCIPLRFVEIHMIN 202
            |..:||..:      |..:..|.|...:.|:.:  |.|.:  ..:...:.:...|.....:.:|.
Zfish   132 LQKDCDRQSERLGRNIESITMVYDCEGLGMKHL--YKPAIETYGEVLTMFEDNYPEGLKRLFVIK 194

  Fly   203 MRKEGQTIFNFVTKFLPSKLPFKFVV--HKKSEDLYQHLPRDVMTIEYGG 250
            ..|.....:|.|..||......|.:|  ....|.|.:::..:.:...|||
Zfish   195 APKLFPVAYNLVKHFLSEDTRRKVIVLGSNWQEVLQKYIDPEELPAYYGG 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	35/173 (20%)
sec14l8	NP_001093463.1	CRAL_TRIO_N	13..59	CDD:215024	9/46 (20%)
		SEC14	78..246	CDD:214706	36/177 (20%)
		GOLD_2	304..382	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810