DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	48/254 - (18%)
Similarity:	91/254 - (35%)	Gaps:	57/254 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IATIKTWITKSPHLKAPTDEQLILAFLRRCRFSQEETKRRFDNYYSLRSVFPEVLGSRQVDEALL 95
            :..::.|:.::...|.|.||. ||.|||...|..::.:.......|.|.       ..|||..|.
  Rat   246 LVQLRRWLQETHKGKIPKDEH-ILRFLRARDFHLDKARDMLCQSLSWRK-------QHQVDLLLQ 302

  Fly    96 TQLQRGIHVIPMRPVSP--------------EGPRVIISQFRNIDPK---KSNPREAFKLIFIML 143
            |          .||.:|              :|..:.|.:...:|.|   |:...||     ::.
  Rat   303 T----------WRPPAPLQEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEEA-----LLQ 352

  Fly   144 ELLAL------ECD------NAAISGLIWVVDARDVTMEQMMQYDPFLLKKAFALVDQCIPLRFV 196
            .:|::      .|:      ...||....::|...:.|..:.:.....|.:...:|:...|....
  Rat   353 HVLSVNEEGQKRCEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLG 417

  Fly   197 EIHMINMRKEGQTIFNFVTKFLPSKLPFKFVVHKKSE-----DLYQHLPRDVMTIEYGG 250
            .:.::...:....::..|:.|:......||:::..|.     .|..:|.:||:....||
  Rat   418 RLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVIPDFLGG 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	31/190 (16%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	20/80 (25%)
		CRAL_TRIO_N	243..288	CDD:215024	11/42 (26%)
		CRAL_TRIO	314..477	CDD:306996	27/168 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900