DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10300 and SEC14L3

DIOPT Version :9

Sequence 1:NP_651174.2 Gene:CG10300 / 42798 FlyBaseID:FBgn0039107 Length:311 Species:Drosophila melanogaster
Sequence 2:XP_011528430.1 Gene:SEC14L3 / 266629 HGNCID:18655 Length:412 Species:Homo sapiens


Alignment Length:288 Identity:49/288 - (17%)
Similarity:99/288 - (34%) Gaps:81/288 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MANTLRTLDPKLA-ALAKSECNEEQAQRAEIIATIKTWITKSPHLKAPTDEQLILAFLRRCRFSQ 64
            |:..:..|.||.| .|||...|.:..               .|.|..| |:..:|.:||...|..
Human     1 MSGRVGDLSPKQAETLAKFRENVQDV---------------LPALPNP-DDYFLLRWLRARNFDL 49

  Fly    65 EETKRRFDNYYSLRSVFPEVLGSRQVDEALLTQLQRGIHVIPMRP-------------------- 109
            ::::.....|...|.       :..:|           |::..:|                    
Human    50 QKSEALLRKYMEFRK-------TMDID-----------HILDWQPPEVIQKYMPGGLCGYDRDGC 96

  Fly   110 ------VSPEGPRVIISQFRNIDPKKSNPREAFKLIFIMLELLALECD------NAAISGLIWVV 162
                  :.|..|:.::......|..|:..|:..:::.        |||      ...|..::.:.
Human    97 PVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILH--------ECDLQTERLGKKIETIVMIF 153

  Fly   163 DARDVTMEQMMQYDPFLLKKAFALVDQCIP--LRFVEIHMINMRKEGQTIFNFVTKFLPSKLPFK 225
            |...:.::...:....:.::.|.|:::..|  |:|:.|  :...|.....:|.:..||......|
Human   154 DCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLI--VKATKLFPVGYNLMKPFLSEDTRRK 216

  Fly   226 FVV--HKKSEDLYQHLPRDVMTIEYGGT 251
            .:|  :...|.|.:.:..:.:..::|||
Human   217 IIVLGNNWKEGLLKLISPEELPAQFGGT 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10300NP_651174.2 SEC14 95..251 CDD:238099 27/191 (14%)
SEC14L3XP_011528430.1 CRAL_TRIO_N 13..59 CDD:215024 13/61 (21%)
SEC14 76..245 CDD:214706 28/179 (16%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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