DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and Ttpa

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_037180.1	Gene:	Ttpa / 25571	RGDID:	3915	Length:	278	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	72/269 - (26%)
Similarity:	116/269 - (43%)	Gaps:	23/269 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LDPKLAALAKSECNEEQAQRAEIIATIKTWITKSPHLKAPTDEQLILAFLRRCRFSQEETKRRFD 72
            :.|.||.|.:      :||...:           |....|..:..:|.|||...|..:...|...
  Rat    24 VQPGLAELRR------RAQEEGV-----------PETPQPLTDAFLLRFLRARDFDLDLAWRLMK 71

  Fly    73 NYYSLRSVFPEVLGSRQVDEALLTQLQRGIHVIPMRPVSPEGPRVIISQFRNIDPKKSNPREAFK 137
            |||..|:..|| |.:.....::|..|:.|.|.: :|...|.|.||:|.:....|||.....:.|:
  Rat    72 NYYKWRAECPE-LSADLHPRSILGLLKAGYHGV-LRSRDPTGSRVLIYRISYWDPKVFTAYDVFR 134

  Fly   138 LIFIMLELLALECDNAAISGLIWVVDARDVTMEQMMQYDPFLLKKAFALVDQCIPLRFVEIHMIN 202
            :..|..||:..|.:... :|:..:.|.....:....|..|.:.||..|:|....||:...||:||
  Rat   135 VSLITSELIVQEVETQR-NGVKAIFDLEGWQISHAFQITPSVAKKIAAVVTDSFPLKVRGIHLIN 198

  Fly   203 MRKEGQTIFNFVTKFLPSKLPFKFVVHKKS--EDLYQHLPRDVMTIEYGGTNGYQAEAVDHWRQK 265
            .......:|:.:..||..|:..:..:|..:  ..|.||.| |::.:||||......:....|...
  Rat   199 EPVIFHAVFSMIKPFLTEKIKGRIHLHGNNYKSSLLQHFP-DILPLEYGGNESSMEDICQEWTNF 262

  Fly   266 LLDSKDYLA 274
            ::.|:|||:
  Rat   263 IMKSEDYLS 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	45/157 (29%)
Ttpa	NP_037180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		CRAL_TRIO_N	25..73	CDD:215024	14/64 (22%)
		CRAL_TRIO	99..248	CDD:395525	43/151 (28%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	208..211		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920