DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and AgaP_AGAP001109

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_322055.4	Gene:	AgaP_AGAP001109 / 1282054	VectorBaseID:	AGAP001109	Length:	709	Species:	Anopheles gambiae

Alignment Length:	261	Identity:	56/261 - (21%)
Similarity:	95/261 - (36%)	Gaps:	63/261 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IATIKTWI------TKSPHLKAPTDEQLILAFLRR--------CRFSQEETKRRFDNYYSLRSVF 81
            :..:|.:|      :..|:.||.|........|.|        ..:.|.|..|:.:..|
Mosquito     9 LKAVKQFIDRINSSSNDPNRKAVTPAIATRFLLARKYDITRAMALYEQHELIRQREGLY------ 67

  Fly    82 PEVLGSRQVDEALLTQLQRG-IHVIPMRPVSPEGPRVIISQFRNIDPKKSNPREAFKLIFIMLEL 145
                |.....|.|.|:|:.| ..::|.|..|  |..:.:.......|.....:...:.:...|:
Mosquito    68 ----GFDPQTEPLRTELETGKFTILPGRDAS--GAAIALFTANLHYPMTVTHKTTLQGVVYQLD- 125

  Fly   146 LALECDNAAISGLIWVVDARDVTMEQMMQYDPFLLKKAFALVDQCIPLRFVEIHMINMRKEGQTI 210
            :||:......:||:::.   |::..:...:|..|.:|...|:....|.|..::.:
Mosquito   126 VALQSSETQKAGLVFIY---DMSTSKYSNFDYDLSQKILTLLKGGYPARLKKVLI---------- 177

  Fly   211 FNFVTKFLPSKLPFK----FVVHKKSEDLYQ--------HLPRDVMTIEYGGTNGYQAEAVDH-- 261
               ||..|..|.|||    ||..|..|.::.        |:||:.:.:..|||     ..|||
Mosquito   178 ---VTAPLWFKAPFKILRLFVREKLRERVFTVSIPQLSLHVPRESLPVRLGGT-----LEVDHSS 234

  Fly   262 W 262
            |
Mosquito   235 W 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	35/168 (21%)
AgaP_AGAP001109	XP_322055.4	CRAL_TRIO	83..227	CDD:279044	33/162 (20%)
		PTPc	414..685	CDD:214550
		PTPc	442..685	CDD:238006
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910