DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10301 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_651173.2	Gene:	CG10301 / 42797	FlyBaseID:	FBgn0039106	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	59/315 - (18%)
Similarity:	111/315 - (35%)	Gaps:	82/315 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IIILRVWIRQQPHLRARTDVDFLIAFLRRCRYSLEETKRRIDRYFT-----HYNLFPEIMNNRCV 87
            ::.||.|: |:.|.......:.::.|||...:.|::.:..:.:..:     ..:|..:.......
  Rat   246 LVQLRRWL-QETHKGKIPKDEHILRFLRARDFHLDKARDMLCQSLSWRKQHQVDLLLQTWRPPAP 309

  Fly    88 TQRLLDINRMGVCLYPDMPKGDSRSAMFIARFGHFDPNLYMLREIYHFSSMAMEVIALENDYASL 152
            .|...    .|...|.|:   |.| .::|.|.|..|..  .|.:.....::...|:::..:....
  Rat   310 LQEFY----AGGWHYQDI---DGR-PLYILRLGQMDTK--GLMKAVGEEALLQHVLSVNEEGQKR 364

  Fly   153 AGICE---------------IIDLEGVNSDKMRRFDRVLFRKWWNWLYNCSPLKVKEMYIINMPK 202
               ||               ::||||:|.       |.|:|.....|     |::.|:...|.|:
  Rat   365 ---CEGNTRQFGRPISSWTCLLDLEGLNM-------RHLWRPGVKAL-----LRMIEVVEDNYPE 414

  Fly   203 DIQGTVMF---------LYNVLSMQVNYPIR----VLKNSE-----ELIEHIGKESLPEEYGGTN 249
            .: |.::.         |:.::|..:|...|    :...|.     .|::::.|:.:|:..||
  Rat   415 TL-GRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVIPDFLGG-- 476

  Fly   250 GHLGECVAYMEDLLNSYRGYFEQDCNYGTIEELRHGE-----IATYEAEFGANGS 299
                      |.:.|...|.......|.|.||....:     ..||.:.....||
  Rat   477 ----------ESVCNVPEGGMVPKSLYLTEEEQEQADQLRQWSETYHSASVLRGS 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10301	NP_651173.2	CRAL_TRIO_N	25..71	CDD:215024	9/42 (21%)
CG10301	NP_651173.2	CRAL_TRIO	114..248	CDD:279044	31/166 (19%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	10/63 (16%)
		CRAL_TRIO_N	243..288	CDD:215024	9/42 (21%)
		CRAL_TRIO	314..477	CDD:306996	37/200 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900