DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10301 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_651173.2	Gene:	CG10301 / 42797	FlyBaseID:	FBgn0039106	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_446253.2	Gene:	Sec14l2 / 116486	RGDID:	621779	Length:	403	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	71/273 - (26%)
Similarity:	110/273 - (40%)	Gaps:	65/273 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LSP----TLAKLAEQEVNETPDRIQQDIIILRVWIRQQPHLRART-DVDFLIAFLRRCRYSLEET 64
            |||    .|||..|...:..|.....|...|..|      ||||: |:....|.||:   .:|..
  Rat     8 LSPKQEEALAKFRENVQDVLPALPNPDDYFLLRW------LRARSFDLQKSEAMLRK---HVEFR 63

  Fly    65 KRR-IDRYFTHYNLFPEIMNNRCVTQRLLDINRMGVCL------YPDMPKGDSRSAMFIA----- 117
            |:: ||:..:...  ||::      |:.|...|.|..|      |..:...|::..:|.|
  Rat    64 KQKDIDKIISWQP--PEVI------QQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL 120

  Fly   118 -RFGHFDPNLYMLREIYHFSS---MAMEVIALENDYASLAGICEIIDLEGVNSDKMRRFDRVLFR 178
             |....|..| :|:|..|.::   ..:|.|.:..|       ||.:.|:.:....:..:...|..
  Rat   121 LRTKMRDCEL-LLQECTHQTAKLGKKIETITMIYD-------CEGLGLKHLWKPAVEAYGEFLTM 177

  Fly   179 KWWNWLYNCSPLKVKEMYIINMPKDIQGTVMF--LYNV----LSMQVNYPIRVLKNS--EELIEH 235
            ...|:     |..:|.::::..||      :|  .||:    ||......|.||..:  |.|::|
  Rat   178 FEENY-----PETLKRLFVVKAPK------LFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKH 231

  Fly   236 IGKESLPEEYGGT 248
            |..:.||.|||||
  Rat   232 ISPDQLPVEYGGT 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10301	NP_651173.2	CRAL_TRIO_N	25..71	CDD:215024	15/47 (32%)
CG10301	NP_651173.2	CRAL_TRIO	114..248	CDD:279044	37/150 (25%)
Sec14l2	NP_446253.2	CRAL_TRIO_N	13..59	CDD:215024	16/54 (30%)
		SEC14	76..244	CDD:214706	46/194 (24%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810