Protein Alignment Gba1a and gba-3

DIOPT Version :9

• Sequence 1: NP_651172.1
• Gene: Gba1a / 42796
• FlyBaseID: FBgn0051148
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001255965.1
• Gene: gba-3 / 178535
• WormBaseID: WBGene00008706
• Length: 525
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 164/533 - (30%)
• Similarity: 265/533 - (49%)
• Gaps: 64/533 - (12%)

  Fly    40 VCVCTADYCDYLENPVLTDENEWFLISSSKQGLRFSTTSDKFGKEEKFTVQDYVEPTQETANATI 104
            ||||.|.:||.:|......|.:..:..||..|.|....|.|.  :||
 Worm    41 VCVCNATFCDEIEPIGEIAEGKAIVYRSSLDGDRLKRMSMKM--KEK------------------ 85

  Fly   105 LSRLLDKVVDSAFTLESRESSITRTVTLRLDRSKTHQKMVGFGGSYTGAVEYLVENFKHSELADH 169
                          |...||.   .||:.:|.|:..|.:.||||::|.:......:...: |.::
 Worm    86 --------------LRKNESV---NVTITIDASERFQNIFGFGGAFTDSAGDQFVSLSET-LQNY 132

  Fly   170 LYKSFYAEDGLGFNLMRVSIGGCDFDLEPWSYAEEEGDTELSDMDELNAHDV-TRVAQIKRLIE- 232
            :..|::.::||.:|:.||.|..|||....:||.:...|.||... .|...|: .::..||:.||
 Worm   133 IVDSYFGKNGLEYNIGRVPIASCDFSTHEYSYDDVHDDFELKHF-ALPDEDLKLKIPFIKKAIEK 196

  Fly   233 VSGVKNLLVKGAAWSSPPWMKTNNRWTGFGRLK--RAYYQTWADYHLRWLRLMKDNGIPIWAIST 295
            ..|  |:.:..:.||:|.|||...|..|.|.::  :..||.:|||..::......:.|..|.::.
 Worm   197 TEG--NIQLFASPWSAPGWMKVTGRMRGGGAMRNDKRVYQAYADYFFKFFEAYSSHAITFWGLTI 259

  Fly   296 GNEPLNGIIFMYFVKFMSLGWTPQTQAIWLNDYLGPTIRNSEFKD-ITLFGNDDQRYSFPHWFKM 359
            .|||..|....:  ::.::.:|.:|...:|..||||.::.::..: :.:...||.|...|.|...
 Worm   260 QNEPSTGADMAW--RWQTMNYTAETMRDFLKKYLGPKLKENKLTETLKVMVLDDGRGLLPGWADT 322

  Fly   360 MNRTRPNSIDYLDGLSLHWYWDEIFGNSF-----IEQTKEYAPDKILIVSESCIGDKPWQAAAPL 419
            :... |.:..|.||:::|||     ||.:     ::.|:.:.|.|.:..:|:|.|  .:....|:
 Worm   323 IFND-PEATKYADGVAVHWY-----GNLYSPAVLLDITQRHHPTKFIFGTEACAG--YFGHHGPI 379

  Fly   420 LGSWERAEKYARDYLLNIKLGFHGWIDWNICLDEIGGPNYVDNTVDAPVIVNTTTFEEFYKQPMF 484
            :|.|.|||.||.|.:.::.....||.|||:||||.||||:..|.||:|:|||.|. :||||||||
 Worm   380 MGDWFRAESYADDIITDLNHHVTGWTDWNLCLDETGGPNWAYNVVDSPIIVNRTA-QEFYKQPMF 443

  Fly   485 YAIGHFSKWVPEGSVRI-DAVPSNVNLDSVAFLRPDNKITAVLFNSGRADLDITLVDSIRG-QFV 547
            ||:|||||::|.||.|: ..:..|:.:.:.:.:....:...|:.:.....|...:|||..| ..|
 Worm   444 YALGHFSKFLPRGSTRVFTKIEGNLAVSATSVVIEGGRRATVILSKASNSLLTRIVDSSTGFSIV 508

  Fly   548 VNVPAKSIHTLLY 560
            :|:|.:||||:::
 Worm   509 LNLPPRSIHTVIW 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gba1a	NP_651172.1	Glyco_hydro_30	29..558	CDD:304972	163/529 (31%)
gba-3	NP_001255965.1	Glyco_hydro_30	28..521	CDD:304972	164/531 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166006
Domainoid	1	1.000	225	1.000	Domainoid score	I1442
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I1794
Isobase	1	0.950	-	0	Normalized mean entropy	S4252
OMA	1	1.010	-	-		QHG62715
OrthoDB	1	1.010	-	-		D206521at33208
OrthoFinder	1	1.000	-	-		FOG0004266
OrthoInspector	1	1.000	-	-		mtm4803
orthoMCL	1	0.900	-	-		OOG6_102859
Panther	1	1.100	-	-	O	PTHR11069
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3226
SonicParanoid	1	1.000	-	-		X3004
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.890