Protein Alignment Gba1a and gba-1

DIOPT Version :9

• Sequence 1: NP_651172.1
• Gene: Gba1a / 42796
• FlyBaseID: FBgn0051148
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001040750.1
• Gene: gba-1 / 173574
• WormBaseID: WBGene00016335
• Length: 523
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 163/584 - (27%)
• Similarity: 259/584 - (44%)
• Gaps: 94/584 - (16%)

  Fly     1 MGKMFASRGMLVLGVLLVSAIGGQSESIPCKLIDAEHGKVCVCTADYCDYLENPVLTDENEWFLI 65
            |...|..:..:.|.|..|.::    .:..|.....:.|.||||:.|.||.:. |:.....:..|.
 Worm     1 MKSRFLLKIFIFLAVFGVDSV----RAADCTEKTFKTGTVCVCSLDSCDEIP-PLDITMGQAALY 60

  Fly    66 SSSKQGLR------FSTTSDKFGKEEKFTVQDYVEPTQETANATILSRLLDKVVDSAFTLESRES 124
            ::|..|.|      ::|.::.||
 Worm    61 TTSHTGARLHRDVIYATDTEPFG------------------------------------------ 83

  Fly   125 SITRTVTLRLDRSKTHQKMVGFGGSYTGAVEYLVENFKH--SELADHLYKSFYAEDGLGFNLMRV 187
                |:.:.:|.||.:|.:.|||.:::.|..   .|.|.  .:|:|.:.|.::::.||.....||
 Worm    84 ----TLHMTIDSSKKYQTIQGFGSTFSDASG---ANLKSLPDKLSDLIMKQYFSDTGLNLQFGRV 141

  Fly   188 SIGGCDFDLEPWSYAEEEGDTELSDMDELNAHDVTRVAQIKRLIEVSGVKNLLVKGAAWSSPPWM 252
            .|...||....:||.:...|..:.:.:........::..||...:.:  .||.:..|.|::|.|:
 Worm   142 PIASTDFSGRVYSYNDVANDYSMQNFNLTKEDFQWKIPYIKNAQKYN--PNLKLFAAPWAAPGWL 204

  Fly   253 KTNNRWTGFGRLKRA----YYQTWADYHLRWLRLMKDNGIPIWAISTGNEPLNGIIFMYFVKFMS 313
            ||....||.|.|...    |:|.:|.|.:|:|.....:||..|.:||.|:|..|.....  |..|
 Worm   205 KTTKEMTGPGALNGKAGDNYHQAYAKYFVRFLEEYGKSGISFWGLSTQNQPTLGSDKKN--KIQS 267

  Fly   314 LGWTPQTQAIWLNDYLGPTI-RNSEFKDITLFGNDDQRYSFPHWFKMMNRTRPNSID---YLDGL 374
            ..:|.:||..::...|||.: .:|..||:.|...||.|.:.|.|..    |..|.:|   |:.|:
 Worm   268 TLFTAETQRDFIKTDLGPALAASSSGKDVKLLILDDNRGNLPKWAD----TVLNDMDAAKYVGGI 328

  Fly   375 SLHWYWDEIFGNSFIEQTKEYAPDKILIVSESC--IGDKPWQAAAPLLGSWERAEKYARDYLLNI 437
            .:|.|.|....| .:::|.:..|:..::.:|:.  .|.|.....   .|:|:||...|.|.|.|:
 Worm   329 GVHAYQDGETDN-HLDETHKKHPNFFILGTEASEGYGSKDTHVD---YGNWDRAADTASDILDNM 389

  Fly   438 KLGFHGWIDWNICLDEIGGPNYVDNTVDAPVIVNTTTFEEFYKQPMFYAIGHFSKWVPEGSVRID 502
            .....||.:.|:.||.:|||::|.:..|||||. .....:||||||||||.|||.::..|:||||
 Worm   390 NNWMTGWTERNLILDALGGPSWVSDYTDAPVIA-FPAMAQFYKQPMFYAIAHFSHFIKPGAVRID 453

  Fly   503 AVPSNVNL--DSVAFLRPDNKITAVLFNSGR-ADLDITLV-----DSIRGQFVVNVPAKSIHTL 558
            ...:.:.|  ::.|||.||.....|:.|.|. ...:.|:|     || |..:...:|.::|.||
 Worm   454 HSLNVIELEVETTAFLNPDGSKVIVMLNKGSLVSTEHTVVVQDAADS-RNHYHFTLPHRAITTL 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gba1a	NP_651172.1	Glyco_hydro_30	29..558	CDD:304972	156/554 (28%)
gba-1	NP_001040750.1	Glyco_hydro_30	23..519	CDD:110998	158/558 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166007
Domainoid	1	1.000	225	1.000	Domainoid score	I1442
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I1794
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62715
OrthoDB	1	1.010	-	-		D206521at33208
OrthoFinder	1	1.000	-	-		FOG0004266
OrthoInspector	1	1.000	-	-		mtm4803
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3004
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.910