DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VAChT and LOC733714

DIOPT Version :9

Sequence 1:	NP_477138.1	Gene:	VAChT / 42795	FlyBaseID:	FBgn0270928	Length:	578	Species:	Drosophila melanogaster
Sequence 2:	NP_001037956.1	Gene:	LOC733714 / 733714	-ID:	-	Length:	425	Species:	Xenopus tropicalis

Alignment Length:	468	Identity:	147/468 - (31%)
Similarity:	237/468 - (50%)	Gaps:	79/468 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 NQRRLILVIVSIALLLDNMLYMVIVPIIPD--YLREIGS------FDDGPTPPPLRDNITGKIIP 85
            :.|.|||.:|::|:::|.:|:.::.||.|.  |..|.|:      .::.......||:|......
Frog    10 DSRWLILFVVAVAMVMDYILFTIVAPIAPALLYDTEYGNRNTTVLLNNSSGSSLYRDSIINNTES 74

  Fly    86 V--------HHDHHGQDSA-TGILFASKAIVQLMVNPFSGGLIDKIGYDLPMMIGLTIMFFSTAV 141
            .        ..|:..:::. .|:|.|.||::||:.||..|.:|::.|||.|:..|..|||.||.:
Frog    75 AGNQTQCYEEKDYLNEENVLVGLLLAIKALLQLLTNPIVGKIINRTGYDAPLFCGTIIMFLSTLM 139

  Fly   142 FACGSSYSVLFFARSLQGAGSAFADTAGLAMIADRFTEENERSQALGIALAFISFGCLVAPPFGG 206
            ||...||:.|..||.|||.||:|.....|.|:|..|.::.||.:|:||||:.::.|.|..||||.
Frog   140 FAFADSYAFLCVARGLQGIGSSFTAVPALGMLAHVFPDDAERGKAMGIALSGVAIGVLAGPPFGS 204

  Fly   207 ALYQFAGKEVPFLILALVCLLDGLMLLLVMKPVKEAMKQSKDVQDQVIPIWRLLMDPYIAVCAGA 271
            |:|:|.||..|||.:|.:.||||::.|.:::|.:     ...|.....|...|||||||.|.|..
Frog   205 AMYEFVGKSAPFLAIAALALLDGVLQLCILRPTR-----FSTVDVPATPYKNLLMDPYILVAAVG 264

  Fly   272 LTMSNVALAFLEPTISLWMEDNMTTDNWKIGMVWLPAFFPHVLGVVITVKMARKYPQHQWLMAAG 336
            |.:.|:....||.|:.:.|.:.|....:::|:.:||....:.:.:.:..::|:|         .|
Frog   265 LCICNLTFGMLETTLPIRMMETMCAPRYQLGLCFLPCIVAYFICLNVFAELAQK---------IG 320

  Fly   337 GLALEGFSCFIIPFCSGYKMLMLPICVICFGIALIDTALLPTLGYLVDVRYVSVYGSIYAIADIS 401
            ..||.                        .|..:::|:::|.:.:|||:|:.|.||.||||:||:
Frog   321 SAALG------------------------IGFGMMETSVMPLMAHLVDLRHTSNYGGIYAISDIA 361

  Fly   402 YSIAYAVGPIIAGGVVEAIGFTALNFLIAFSNLAYVPVLRKLRNIYDFKPFENEANILMQDPPNK 466
            ..|.||:||...|.:.:|:||..|..::...||.:.|:.                 ||:::||.|
Frog   362 LCIGYALGPSCGGAIAKAVGFKWLMIILGIINLVFAPLF-----------------ILLRNPPGK 409

  Fly   467 EYQTYVMHDQKPV 479
            |       :.||:
Frog   410 E-------ETKPL 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VAChT	NP_477138.1	MFS_1	88..410	CDD:284993	112/322 (35%)
VAChT	NP_477138.1	2_A_01_02	98..238	CDD:273318	65/139 (47%)
LOC733714	NP_001037956.1	MFS_1	94..370	CDD:284993	111/313 (35%)
LOC733714	NP_001037956.1	2_A_01_02	96..237	CDD:273318	65/140 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59108
OrthoDB	1	1.010	-	-		D406900at33208
OrthoFinder	1	1.000	-	-		FOG0000700
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930