Protein Alignment VAChT and cat-1

DIOPT Version :9

• Sequence 1: NP_477138.1
• Gene: VAChT / 42795
• FlyBaseID: FBgn0270928
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: NP_001024936.1
• Gene: cat-1 / 180837
• WormBaseID: WBGene00000295
• Length: 553
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 180/559 - (32%)
• Similarity: 289/559 - (51%)
• Gaps: 121/559 - (21%)

  Fly    29 NQRRLILVIVSIALLLDNMLYMVIVPIIPDYL--------------------------------- 60
            |.|:::|:||.|||.|||||...:|||||:||
 Worm    13 NNRKILLLIVYIALFLDNMLLTTVVPIIPEYLLRMEHPNETDILFSHNSQKRVKRQWEDDDSWDV 77

  Fly    61 -REIGS-----FDDGPTPPPLRD-------------------------NITGKIIPV-------- 86
             .::|:     :|:.|..|..|.                         :...|..||
 Worm    78 PLKLGNNADIDWDENPIGPVGRSERRKESDRKNHNSKNREYNDRRKYMSPAAKKPPVETEEPAVR 142

  Fly    87 ---HHDHH----GQDSATGILFASKAIVQLMVNPFSGGLIDKIGYDLPMMIGLTIMFFSTAVFAC 144
               ..:.|    .::...|::|.|||:|||:|||:.|.|.::|||.:||..|..|||.||.:||.
 Worm   143 TISEEERHKLLASENVHVGLMFGSKALVQLLVNPWIGPLTNRIGYTMPMFGGFVIMFCSTILFAF 207

  Fly   145 GSSYSVLFFARSLQGAGSAFADTAGLAMIADRFTEENERSQALGIALAFISFGCLVAPPFGGALY 209
            |.||..|:.||:|||.|||...|:|:.|:|..:.::.||..|:||||..::.|.||.||:||.||
 Worm   208 GDSYFTLWLARALQGVGSACTSTSGMGMLAQAYPDDLERGSAMGIALGGLALGVLVGPPYGGLLY 272

  Fly   210 QFAGKEVPFLILALVCLLDGLMLLLVMKP-VKEAMKQSKDVQDQVIPIWRLLMDPYIAVCAGALT 273
            |::|||:||::|||:.|.||.:..:|::| :.....:...::       :|..||||.|.|||:|
 Worm   273 QWSGKELPFVLLALLALFDGSIQFMVLQPKIDRGEPEGSSIK-------QLAKDPYIIVAAGAIT 330

  Fly   274 MSNVALAFLEPTISLWMEDNMTTDNWKIGMVWLPAFFPHVLGVVITVKMARKYPQHQWLMAAGGL 338
            :.|:.:|.|||::.|||.::...::.:.|..:|||...:::|..|...:|.:.  .:||.:..||
 Worm   331 IGNLGIAMLEPSLPLWMMESWGANSLERGAAFLPASISYLIGTNIFGPLAHRI--GRWLSSFIGL 393

  Fly   339 ALEGFSCFIIPFCSGYKMLMLPICVICFGIALIDTALLPTLGYLVDVRYVSVYGSIYAIADISYS 403
            .:.|||...||..:....|::|..::.|.|.:||.::.|.:|||||:|:|.||||||||||.::.
 Worm   394 VVIGFSLLSIPSATSVAGLIIPHALLGFSIGMIDASMFPLMGYLVDIRHVGVYGSIYAIADAAFC 458

  Fly   404 IAYAVGPIIAGGVVEAIGFTALNFLIAFSNLAYVPVLRKLRNIYDFKPFENEANILMQDPPNKEY 468
            .|:|:||..:|.:|:::||..:.::||..:..|.|::                 .|:::||
 Worm   459 FAFALGPFFSGPLVKSLGFPTMMYIIAVISFLYAPLM-----------------FLLKNPP---- 502

  Fly   469 QTYVMHDQKPVEGGVKNHLEYGQQYQQEQETNLDDQQYE 507
               |:.:..|....|        :.:|..::.:.::.||
 Worm   503 ---VLIEPTPQTQSV--------ELRQNGDSRVTNENYE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VAChT	NP_477138.1	MFS_1	88..410	CDD:284993	133/326 (41%)
		2_A_01_02	98..238	CDD:273318	71/139 (51%)
cat-1	NP_001024936.1	MFS_SLC18A1_2_VAT1_2	18..499	CDD:340942	170/506 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59108
OrthoDB	1	1.010	-	-		D406900at33208
OrthoFinder	1	1.000	-	-		FOG0000700
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2004
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960