Protein Alignment VAChT and LOC100496053

DIOPT Version :10

• Sequence 1: NP_477138.1
• Gene: VAChT / 42795
• FlyBaseID: FBgn0270928
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: XP_002932792.2
• Gene: LOC100496053 / 100496053
• XenbaseID: XB-GENE-29082975
• Length: 494
• Species: Xenopus tropicalis
• Alignment Length: 496
• Identity: 169/496 - (34%)
• Similarity: 265/496 - (53%)
• Gaps: 68/496 - (13%)

  Fly    21 W--EKIQEPVNQRRLILVIVSIALLLDNMLYMVIVPIIPDYLREIGSFDD--------GPTPPPL 75
            |  ||.:.|    .|:||:|.:||||||:|..::||:|||||.| ..|.:        ...|.|.
 Frog    18 WLKEKRESP----HLVLVVVFLALLLDNLLLTIVVPVIPDYLYE-SEFVNKTAVEAKMSSIPAPD 77

  Fly    76 RDNITGKIIPVHH------DHH--------------------GQDSATGILFASKAIVQLMVNPF 114
            ..:...:::...:      |.|                    .::...|:|.|||::|.::|||.
 Frog    78 SSSFLSRLLYYRYNELLFSDEHENSTKGLLKEPCRKDTNFLRDENVPVGLLIASKSMVHILVNPI 142

  Fly   115 SGGLIDKIGYDLPMMIGLTIMFFSTAVFACGSSYSVLFFARSLQGAGSAFADTAGLAMIADRFTE 179
            .....:::||.|||..|..||..|..:||.|.||..|..||.|||.||:|...|||.|:|..:|:
 Frog   143 VSLFTNRVGYGLPMFFGFLIMLMSIFMFAFGGSYVFLLLARMLQGIGSSFTVVAGLGMVASIYTD 207

  Fly   180 ENERSQALGIALAFISFGCLVAPPFGGALYQFAGKEVPFLILALVCLLDGLMLLLVMKP-VKEAM 243
            :.:|.:|:||||..:..|.:..||||.|||:|.||..|||.||.:.||||.:.|.::.| :..|:
 Frog   208 DYQRGKAMGIALGGVVLGVVAGPPFGSALYEFVGKASPFLFLAALALLDGALQLFILTPKISPAV 272

  Fly   244 KQSKDVQDQVIPIWRLLMDPYIAVCAGALTMSNVALAFLEPTISLWMEDNMTTDNWKIGMVWLPA 308
            .....       ...||.||||.|.||.|.::::.:..||||:.:||..:|.:.:|:||:|:|||
 Frog   273 TTPPS-------FCSLLKDPYILVAAGCLCIASMGIGMLEPTLPIWMLGSMCSPDWQIGLVFLPA 330

  Fly   309 FFPHVLGVVITVKMARKYPQHQWLMAAGGLALEGFSCFIIPFCSGYKMLMLPICVICFGIALIDT 373
            ...:::...:...::.|:  .:||.:..|:.|.|.....:|.......|:.||..|...:.::|:
 Frog   331 SLSYLVCTNVFGILSHKF--GRWLCSLLGMVLLGICLLCMPLAFNILGLIAPIAGIGVSLGIVDS 393

  Fly   374 ALLPTLGYLVDVRYVSVYGSIYAIADISYSIAYAVGPIIAGGVVEAIGFTALNFLIAFSNLAYVP 438
            :::|.:|||||:|:.||||.:|||:||::|..||:||..||.:.:||||..|..:|...|:.|.|
 Frog   394 SIMPIMGYLVDLRHSSVYGGVYAISDIAFSFGYAIGPSAAGAIAKAIGFPMLMVIIGVLNIIYCP 458

  Fly   439 VLRKLRNIYDFKPFENEANILMQDPPNKEYQTYVMHDQKPV 479
            :.                 :|:::||.||.:..:::.:..|
 Frog   459 LC-----------------VLLRNPPMKEERRALLNHESIV 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VAChT	NP_477138.1	MFS_SLC18A3_VAChT	35..444	CDD:340941	158/443 (36%)
LOC100496053	XP_002932792.2	MFS_SLC18A1_2_VAT1_2	116..464	CDD:340942	136/373 (36%)