DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10254 and UBE2Z

DIOPT Version :9

Sequence 1:	NP_651170.1	Gene:	CG10254 / 42793	FlyBaseID:	FBgn0027512	Length:	1398	Species:	Drosophila melanogaster
Sequence 2:	NP_075567.2	Gene:	UBE2Z / 65264	HGNCID:	25847	Length:	354	Species:	Homo sapiens

Alignment Length:	221	Identity:	68/221 - (30%)
Similarity:	107/221 - (48%)	Gaps:	28/221 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1100 LPNAPAAH----------NFISNLITPANKAQYQRAVQREYLMLKSSLPNGVVVRAYEDRMDLMS 1154
            ||.:.|||          ...|:........|....::|:.:.:....|.|:.|  ..|.:|:..
Human    68 LPPSAAAHGAALLSHWDPTLSSDWDGERTAPQCLLRIKRDIMSIYKEPPPGMFV--VPDTVDMTK 130

  Fly  1155 V--MMVGPKRTPYQNALFFFDFQFGRDYPKSPPVCHYIS--YCTDRLNPNLYEGGRVCVSLLGTW 1215
            :  ::.||..|||:...|.|.|:...|||..||....::  ..|.|.|||.|..|:||:|:||||
Human   131 IHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTW 195

  Fly  1216 MGRDNEVWSPSSTMLQVLVSIQGLILVDEPYYNEAGYEKQRGTQLGNENSRVYNEM---AIIKIA 1277
            .|   ..|||:.::..||:|||.| :.:.||:||.|:|::|..    .:|:.|||.   ..|::|
Human   196 TG---PAWSPAQSISSVLISIQSL-MTENPYHNEPGFEQERHP----GDSKNYNECIRHETIRVA 252

  Fly  1278 QSTVKQLTNP-PLIFRNELIEHFKEF 1302
            ...:.:...| |...|..:.:.|.|:
Human   253 VCDMMEGKCPCPEPLRGVMEKSFLEY 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10254	NP_651170.1	UQ_con	1126..1272	CDD:278603	54/152 (36%)
UBE2Z	NP_075567.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		UBCc	103..221	CDD:238117	43/123 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	332..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0895
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1047
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810