Protein Alignment CG10254 and ube2o

DIOPT Version :9

• Sequence 1: NP_651170.1
• Gene: CG10254 / 42793
• FlyBaseID: FBgn0027512
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: XP_031750084.1
• Gene: ube2o / 100327234
• XenbaseID: XB-GENE-877047
• Length: 1283
• Species: Xenopus tropicalis
• Alignment Length: 1497
• Identity: 396/1497 - (26%)
• Similarity: 602/1497 - (40%)
• Gaps: 415/1497 - (27%)

  Fly    60 SHSRRSGGGQVPSKAQGNTESQFF--LEDGVFRIDRRGRVHFGLVTATTETYSSSEEEDV----- 117
            |.|..|.....|....|:....|.  |..|.:    ||...|||| .......|.||||.
 Frog     5 SDSAPSSASPGPPAGDGSQRLLFSHDLVSGCY----RGHTRFGLV-RLIHGEDSEEEEDALPGEE 64

  Fly   118 -----------------------------DSLSRGEVRVAFYPGGKEMVMTEQSIGLADRTLMPG 153
                                         ..|.||.|||.:||.|.:..:.|..:.|.||:|:|.
 Frog    65 ESGPGGRKKGAGGAAGGGSPGSEPPLSRFGPLKRGYVRVQWYPEGIKQDVRENKLKLEDRSLVPR 129

  Fly   154 DVVRRRLPGENVLAGQAGYVRDVNVRADVMVMGSRMVIKNVPAERLR---PISEWNQYVPLCMDT 215
            |||||.    .....|.|.|.|||:...|.|:|:...:..|.::.|.   ||. :..|:  ..|.
 Frog   130 DVVRRM----GTKDSQCGTVIDVNIDCVVKVVGTNCFLHPVNSKELHHIWPIM-YGDYI--AYDC 187

  Fly   216 WIGTIIDINECAVLKSSNGARVEITSNDFHKFKDAVSEC-DRTVF--NPNVFFPGNIVIGRMPPP 277
            |:|.:.|:....|||.|||||..:::.|..|..|..... |..:|  :...|:||.::||    |
 Frog   188 WLGKVYDLKNQVVLKLSNGARCSMSTEDASKLYDVCPHASDSGLFFDDSYGFYPGQVLIG----P 248

  Fly   278 DRV-------KNLTPEITHPLTRKGRAVYTVESVETTSINVDWSCRA--IGNATGSDDTDSDPLK 333
            .:|       ..:.|    .|:.|.:....||.|:.|.:.|.|..::  :|   |:|..|..|
 Frog   249 SKVFSSVQWLSGVKP----VLSAKSKFRVGVEEVQVTELRVTWITKSFCLG---GTDSMDPPP-- 304

  Fly   334 EPRSLIKGEELHKVKRLSLYESYELQIHDR-FYLKYSK-------CDLLVKYADWENEQAEKYIP 390
               ::|..|.|.:||||..::..:.|:.:| .|:..:|       |:.|.|..........:.:.
 Frog   305 ---AVITQENLSRVKRLGSFDHTQRQLGERCLYIFPTKVEPTKILCESLEKNCLLGEVTVTRKVH 366

  Fly   391 IFHAQKKMQRKASKLNASASTSGNARSVPKFRRMPNKISGMRLPRPPSDQTHNACKSSKRSKEDV 455
            ....:|..:::..|:.:......|          |.::.......|||.:...|    :.::||:
 Frog   367 TQQVEKLREKQIVKIISCTQDPSN----------PTELLKKNSTVPPSYEIPTA----RATEEDL 417

  Fly   456 LTSEDEDE-------------------FEEFMQPLD-QSMTAEKEVEVAED-----ALPPSAATT 495
            ::::.|.|                   |.|..|.|. .|...:.:.|.|.|     ::..||::|
 Frog   418 VSAKLEGEPPEEPNVPECPTKEQPLGTFREIFQGLQLHSSEQDADDEAAGDTDETSSVTSSASST 482

  Fly   496 AA------AGVEVQAPRITMRSAKRRQVKKKIRSVKKTIYSPFNKKETTPKDGDEIVVETLVVYS 554
            |:      ||.:...| :::|:.||:..|||    |..:|..|       |.||.:.||.:...:
 Frog   483 ASSQSGSGAGRKKSIP-LSIRNLKRKHKKKK----KSKVYREF-------KHGDRVAVEVITTVT 535

  Fly   555 SVTVVWQDGTVESGVHSTQLYPIHHLDNHEFFPGDFVT-KANDISTGATDYGVIQCVDHDARIAK 618
            :..|:||||:||:.:.|.:|.||.||||:||.|||||. |....:...:.|||:|..||..|...
 Frog   536 TADVMWQDGSVETNIRSNELVPIQHLDNNEFCPGDFVVDKRAHAAQDPSIYGVVQSGDHTGRTCV 600

  Fly   619 VMWFNIYTNIDNPIPLFKGLEELSVYDMKDHTDYQYRPGTVVIRVSNFTGE---DVNS-TAGQVI 679
            |.|..:..|.|: ..|....|::||||:.||.|:::|...:|||:.|...|   |.:. :.|||.
 Frog   601 VKWIKLNLNGDD-TELVGEEEDVSVYDIVDHPDFRFRATDIVIRIGNSDPEAFPDASQPSVGQVA 664

  Fly   680 DNYPNGRVRVWWAKGHITLCYPQDLFQPFEQDEQNEQDQ-DVYGSDGSEDSWETESENSHISSSD 743
            ....:.:|.|.||....|:..||.|:....:.|::..|. |...|..|.|.||.||::....:..
 Frog   665 RVDVSSKVEVIWADNSRTIVLPQHLYNVESELEESFYDSVDSSSSGASSDEWEDESDSWETDNGL 729

  Fly   744 NDDDILTGIDRATEAMKVLEKMFRVLHPNRKAEVLYDLLDVYKNCRALDRLLNTKFFDEFNFKGI 808
            .:|:|                      |.
 Frog   730 TEDEI----------------------PR------------------------------------ 736

  Fly   809 VRCKPITSKVCSDSATHERATPETPETSAAVPKESSTLQAELEPVLMDPSVQSSSSPTKRKSSTE 873
                         :|..|.|.....||:.|.|.:        ||. .|.:.||::
 Frog   737 -------------AAGGEEAAASQNETAPAEPMQ--------EPA-QDEAEQSAA---------- 769

  Fly   874 MDEVLCKKSTDEISEEQDYQVEVVEVIEDPPLVREYRCKYNEMFANARRSIAKAIENRTKNDSGV 938
                        ::...|..|..|:|.|...:|:.:: :..|..     .|.::::|.|....
 Frog   770 ------------LAAAADLGVLGVKVNEKEGIVKSFK-ELKEAI-----KILESLKNMTVEQL-- 814

  Fly   939 HSRGEITSDESNNHPDSENKLDIKHPTINVMDDLEIELVASGDADVCEVFCYLIKFQMARIRKTV 1003
             ..|..||..:.....:..|        ..:||::
 Frog   815 -LTGSPTSPTAEPEKFTREK--------KFLDDIK------------------------------ 840

  Fly  1004 AVTLGKTNDNPKQEKEDVSDAEEAIEAVSQEAELANDGATECNTMAEDEAMEEPLNLNALSESLP 1068
                 |..:|.|:..::|:.|||  |.:....|...:...|..|....|...:...|...|...|
 Frog   841 -----KLQENLKKTLDNVAIAEE--EKMESAPETEKEEKAEAQTPVRSEWPSDTPVLCQQSGGKP 898

  Fly  1069 AIDQTGPMACSSPSWSIIPDTPSVDENCFQVLP-NAPAAHNFISNLITPANKAQYQRAVQREYLM 1132
            .:..|   :.....:|::...|  :...|:.|. .||.|..|.|             .|::|..:
 Frog   899 GVIFT---SAKGEVFSVLETAP--ESQAFKKLEFQAPEAKKFFS-------------TVRKEMAL 945

  Fly  1133 LKSSLPNGVVVRAYEDRMDLMSVMMVGPKRTPYQNALFFFDFQFGRDYPKSPPVCHYISYCTDRL 1197
            |.:|||:|::|:.:||||||.|.::.||.||||::.||.||.|....||..||:..|:|.|:.:|
 Frog   946 LATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLFLFDMQLPNIYPAVPPLFRYLSQCSGKL 1010

  Fly  1198 NPNLYEGGRVCVSLLGTWMGRDNEVWSPSSTMLQVLVSIQGLILVDEPYYNEAGYEKQRGTQLGN 1262
            |||||:.|:|||||||||:|:..|.|:..|::||||:||||||||:||||||||::..||.|.|.
 Frog  1011 NPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGY 1075

  Fly  1263 ENSRVYNEMAIIKIAQSTVKQLTNPPLIFRNELIEHFKEFGTELYARMRAWSE------------ 1315
            ||||.|||||:|::.||..:.|..|..:|:.|:.|||:..|..|..|:..|.|
 Frog  1076 ENSRCYNEMALIRVVQSMTQMLRRPVEVFQQEIREHFQSSGWRLAHRIENWLETNSMVERGGEHR 1140

  Fly  1316 ----------YS-------------------------------------LEAQRQNIT---KIKD 1330
                      ||                                     ||:..:..|   .:.|
 Frog  1141 NGQEHPCIVPYSPTEPECTPEPTLDSKDLDDSGCGASTMSPGESQQFSDLESTSKGATGGASLSD 1205

  Fly  1331 MP-----------------VEYKASCELPE--------FPLLPCSRGFCIAVKRVLSQLQSELTA 1370
            .|                 ..|::.  ||:        |||.|.|:||..:::.||:|.::.|..
 Frog  1206 EPRGAAGGGQPSVKPKKRRKSYRSF--LPDKRGYPDIGFPLFPLSKGFIKSIQGVLAQFKASLLE 1268

  Fly  1371 LG 1372
            .|
 Frog  1269 AG 1270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10254	NP_651170.1	UQ_con	1126..1272	CDD:278603	84/145 (58%)
ube2o	XP_031750084.1	UBCc	939..1089	CDD:238117	87/149 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	435	1.000	Inparanoid score	I1659
OMA	1	1.010	-	-		QHG60077
OrthoDB	1	1.010	-	-		D38527at33208
OrthoFinder	1	1.000	-	-		FOG0005714
OrthoInspector	1	1.000	-	-		oto102498
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1047
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980