DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPE and f10

DIOPT Version :9

Sequence 1:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_001015728.1	Gene:	f10 / 548445	XenbaseID:	XB-GENE-971433	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	298	Identity:	85/298 - (28%)
Similarity:	141/298 - (47%)	Gaps:	52/298 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 LQQGDVLPGNDVCGFLFAD------RIFGGTNTTLWEFPWMVLLQYKKLFSETYTFNCGGALLNS 173
            :.|...||..:|.|....:      ||.||...:..|.||..||    :..|...| |||.:|:.
Frog   202 MNQTGTLPERNVTGINILNPNDPNVRIVGGRECSQGECPWQALL----VSDEDEGF-CGGTILSR 261

  Fly   174 RYVLTAGHCLASRELDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEVEKGIIHEM 238
            .::|||.||:...:..|       |.:||.:|:.. :.|..::            :|||.|:|..
Frog   262 EFILTAAHCMNQTKYFK-------VVVGELNTKIS-EGTESIH------------KVEKIIMHPR 306

  Fly   239 YAPNSVDQRNDIALVRLKRIVSYTDYVRPICLP----TDGLVQNNFVDYGMDVAGWGL--TENMQ 297
            :..::.|.  |||:::||..:::|:.:.|.|:|    .|.::.|   :....|:|:|.  ....|
Frog   307 FVKSTYDY--DIAVIKLKEAINFTENIIPACIPDPEFADQVLMN---EPDAMVSGFGRIHERGRQ 366

  Fly   298 PSAIKLKITVNVWNLTSCQEKYSSFKVKLDDSQMCAGGQLGV-DTCGGDSGGPLMVPISTGGRDV 361
            .|.::: :.|......||:|. |:|.:  .::..|||....| |.|.||||||.:.|.    :..
Frog   367 ASTLQM-LQVPYIKRHSCKES-STFAI--TENMFCAGFDTEVKDACQGDSGGPHVTPF----KGT 423

  Fly   362 FYIAGVTSYGTKPCGLKGWPGVYTRTGAFIDWIKQKLE 399
            :::.|:.|:| :.|..||..||||:......|:|..|:
Frog   424 YFVTGIVSWG-EGCARKGKFGVYTKVSKLHRWLKGVLK 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPE	NP_651168.1	CLIP	42..94	CDD:314844
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	78/268 (29%)
f10	NP_001015728.1	GLA	22..84	CDD:214503
		EGF_CA	85..121	CDD:238011
		FXa_inhibition	128..163	CDD:373209
		Tryp_SPc	228..456	CDD:238113	77/266 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010