DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPE and CG4815

DIOPT Version :9

Sequence 1:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_651607.1	Gene:	CG4815 / 43360	FlyBaseID:	FBgn0039568	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	66/278 - (23%)
Similarity:	105/278 - (37%)	Gaps:	58/278 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 FADRIFGGTNTTLWEF--PWMVLLQYKKLFSETYTFNCGGALLNSRYVLTAGHCLASRELDKSGA 193
            |..||:.|..||:...  ..:.|...:||.       |...||..|::|||.||..:....|...
  Fly    31 FHPRIYNGIKTTVESLGGVGIQLFNGRKLV-------CSATLLTPRHILTAAHCFENLNRSKFHV 88

  Fly   194 VLHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEVEKGIIHEMYAPNSVDQRNDIALVRLK-- 256
            :........|            :|......|.|.::     ||..||  .:....|:|:.:.|
  Fly    89 IGGKSAEFTW------------HGNNFNKNKLIRVQ-----IHPKYA--KMKFIADVAVAKTKYP 134

  Fly   257 ---RIVSYTDYVRPICLPTDGLVQNNFVDYGMDVAGWGLTENMQPSAIK---LKITVNVWNLTSC 315
               :.:.|....|.:..|.|.|:          .||||....:...:.|   ..:.|.:.:...|
  Fly   135 LRSKYIGYAQLCRSVLHPRDKLI----------AAGWGFEGGVWDESRKKTFRSMKVGIVSKRDC 189

  Fly   316 QEKYSSFKVKLDDSQMCAGGQLGVDTCGGDSGGPLMVPISTGGRDVFYIAGVTSYGTKPCGLKGW 380
            :::...   |:..:.:|||.......|.|||||||::     ||.|   .|:.:: |..||....
  Fly   190 EKQLDR---KMPPNIICAGAYNNKTLCFGDSGGPLLL-----GRQV---CGINTW-TFKCGNNEK 242

  Fly   381 PGVYTRTGAFIDWIKQKL 398
            |.||.....:..:||:.:
  Fly   243 PDVYMGVRYYAKFIKRTI 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPE	NP_651168.1	CLIP	42..94	CDD:314844
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	64/271 (24%)
CG4815	NP_651607.1	Tryp_SPc	49..259	CDD:304450	60/257 (23%)
CG4815	NP_651607.1	Trypsin	49..256	CDD:278516	58/254 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436623
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940