DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPE and Jon74E

DIOPT Version :9

Sequence 1:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	93/285 - (32%)
Similarity:	133/285 - (46%)	Gaps:	40/285 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 LQQGDVLPGNDVCGFLFADRIFGGTNTTLWEFPWMVLLQYKKLFSETYTFNCGGALLNSRYVLTA 179
            |.||..:...|: |.....||.||......:||:.|.|..::. ::.|.: ||.:|::.||:|||
  Fly    13 LVQGRSISCLDM-GHGIGGRIAGGELARANQFPYQVGLSIEEP-NDMYCW-CGASLISDRYLLTA 74

  Fly   180 GHCLASRELDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEVEKGIIHEMYAPNSV 244
            .||     ::|:.|:                 |..:.|....||:.: |......:|.....|..
  Fly    75 AHC-----VEKAVAI-----------------TYYLGGVLRLAPRQL-IRSTNPEVHLHPDWNCQ 116

  Fly   245 DQRNDIALVRLKRIVSYTDYVRPICLPTDGLVQN-NFVDYGMDVA-GWGLTENMQPSAI--KLKI 305
            ...||||||||.......|.:|||.||  ||..: |..||...:| ||| ..|.:.:||  .|:.
  Fly   117 SLENDIALVRLPEDALLCDSIRPIRLP--GLSSSRNSYDYVPAIASGWG-RMNDESTAISDNLRY 178

  Fly   306 TVN-VWNLTSCQEKYSSFKVKLDDSQMCAGGQLGVDTCGGDSGGPLMVPISTGGRDVFYIAGVTS 369
            ... |.:...|:..|::.|    .:.:|.....|..||.|||||||:........|:  :.||||
  Fly   179 VYRFVESNEDCEYSYANIK----PTNICMDTTGGKSTCTGDSGGPLVYSDPVQNADI--LIGVTS 237

  Fly   370 YGTKPCGLKGWPGVYTRTGAFIDWI 394
            ||.|....||:|.|:||..|::|||
  Fly   238 YGKKSGCTKGYPSVFTRITAYLDWI 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPE	NP_651168.1	CLIP	42..94	CDD:314844
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	87/265 (33%)
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	86/264 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010