DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPE and CG1299

DIOPT Version :9

Sequence 1:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	380	Identity:	122/380 - (32%)
Similarity:	175/380 - (46%)	Gaps:	67/380 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GQCVHITSCPYLANLLMVEPKTPAQRILLSKSQCGLDNRVEGLVNRILVCCPQSMRGNIMDSEPT 108
            |.||.|..|..|.|.|....:.......|..|.....|:      ...||||...  .|.::.|.
  Fly   172 GNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNK------GTQVCCPTGQ--GITNTTPA 228

  Fly   109 PSTRDALQQGDVLPGN------------DVCGFL--FADRIFGGTNTTLWEFPWMVLLQYKKLFS 159
            ||        .::|.|            :.||..  :..:|.||..:....:||:.||.|..  .
  Fly   229 PS--------QIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDD--P 283

  Fly   160 ETYTFNCGGALLNSRYVLTAGHCLASRELDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICAPK 224
            ....|.|||.|:.:|:||||.||:...        |..|||||.|..||.:            ..
  Fly   284 SGSPFKCGGTLITARHVLTAAHCIRQD--------LQFVRLGEHDLSTDTE------------TG 328

  Fly   225 HIDIEVEKGIIHEMYAPNSVDQRNDIALVRLKRIVSYTDYVRPICLP-TDGLVQNNFVDYGMDVA 288
            |:||.:.:.:.|..|  |..:.|:|:|::.|:|.|.:|..:.||||| |..|.|.::|.|...||
  Fly   329 HVDINIARYVSHPDY--NRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVA 391

  Fly   289 GWGLT-ENMQPSAIKLKITVNVWNLTSCQEKYSSFK-----VKLDDSQMCAG---GQLGVDTCGG 344
            |||.| |..:.:.:..::.:.:::...|.:.|:..|     .:.|.:.:|||   |  |.|||.|
  Fly   392 GWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSG--GKDTCQG 454

  Fly   345 DSGGPLMVPISTGGRDVFYIAGVTSYGTKPCGLKGWPGVYTRTGAFIDWIKQKLE 399
            |||||||:|....|:..||:.||.|||. .|.....||||:.|..|:|||.|:::
  Fly   455 DSGGPLMLPEPYQGQLRFYLIGVVSYGI-GCARPNVPGVYSSTQYFMDWIIQQVQ 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPE	NP_651168.1	CLIP	42..94	CDD:314844	12/49 (24%)
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	98/271 (36%)
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	12/49 (24%)
		Tryp_SPc	260..503	CDD:214473	96/269 (36%)
		Tryp_SPc	261..503	CDD:238113	96/268 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920