DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPE and CG30088

DIOPT Version :9

Sequence 1:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_725488.3	Gene:	CG30088 / 246447	FlyBaseID:	FBgn0050088	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	92/279 - (32%)
Similarity:	134/279 - (48%)	Gaps:	40/279 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 CGFLF----ADRIFGGTNTTLWEFPWMVLLQYKKLFSETYTFNCGGALLNSRYVLTAGHCLASRE 187
            ||..:    |.||..|....|...|:|..|.|.   ||   .:|||.:::|||:|||.||:  |.
  Fly    33 CGVSYESNVATRIVRGKEAMLKSAPFMAYLYYS---SE---IHCGGTIISSRYILTAAHCM--RP 89

  Fly   188 LDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEVEKGIIHEMYAPNSVDQRNDIAL 252
            ..|       |||||.|...:|||   ..|.  |:|...:.::   ::...|........|||||
  Fly    90 YLK-------VRLGEHDITRNPDC---QGGS--CSPPAEEFDI---VLATKYKRFDRFLANDIAL 139

  Fly   253 VRLKRIVSYTDYVRPICLPTDGLVQNNFVDYGMDVAGWGLTENMQPSAIKLKITVNVWNLTSCQE 317
            ::|.|.:.:..:::||||..:.....|..::  ...|||.||. ..||..|:.||    ||....
  Fly   140 LKLSRNIRFNVHIQPICLILNPAAAPNVHEF--QAFGWGQTET-NHSANVLQTTV----LTRYDN 197

  Fly   318 KY--SSFKVKLDDSQMCAGGQLGVDTCGGDSGGPLMVPISTGGRDVFYIAGVTSYGTKPCGLKGW 380
            ::  |...:.:..:|:|.|.| |.|||.|||||||:..::..|...:...|:.|:|...|..
  Fly   198 RHCRSVLSMPITINQLCVGFQ-GSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQS--- 258

  Fly   381 PGVYTRTGAFIDWIKQKLE 399
            |||||....:|.||:..::
  Fly   259 PGVYTYVPNYIRWIRYVMQ 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPE	NP_651168.1	CLIP	42..94	CDD:314844
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	88/263 (33%)
CG30088	NP_725488.3	Tryp_SPc	44..272	CDD:214473	87/261 (33%)
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	87/261 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463540
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840