Protein Alignment SPE and Tmprss4

DIOPT Version :10

• Sequence 1: NP_651168.1
• Gene: SPE / 42791
• FlyBaseID: FBgn0039102
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_663378.1
• Gene: Tmprss4 / 214523
• MGIID: 2384877
• Length: 435
• Species: Mus musculus
• Alignment Length: 441
• Identity: 124/441 - (28%)
• Similarity: 188/441 - (42%)
• Gaps: 105/441 - (23%)

  Fly     9 LLLSLVVSALSGLVHRSDAAEISFGSCTPQQSDERGQ-CVHITSCPY---LANLLMVEPKTPAQR 69
            :||||:...:..|:.:....:..|...:|....:||| |.....|..   ..:.:...|:.|...
Mouse    37 VLLSLIALVIVALLIKVILDKYYFICGSPLTFIQRGQLCDGHLDCASGEDEEHCVKDFPEKPGVA 101

  Fly    70 ILLSKSQCGL---------------DNRVEGLVNRILVCCPQ-------SMRG-------NIMDS 105
            :.|||.:..|               ||..|.|..   ..|.|       :.|.       |:..:
Mouse   102 VRLSKDRSTLQVLDAATGTWASVCFDNFTEALAK---TACRQMGYDSQPAFRAVEIRPDQNLPVA 163

  Fly   106 EPTPSTRD-ALQQG--DVLPGNDV------CG-FLFADRIFGGTNTTLWEFPWMVLLQYKKLFSE 160
            :.|.:::: .:|.|  ..|.|:.|      || .|...|:.||....:..:||.|.:||.|
Mouse   164 QVTGNSQELQVQNGSRSCLSGSLVSLRCLDCGKSLKTPRVVGGVEAPVDSWPWQVSIQYNK---- 224

  Fly   161 TYTFNCGGALLNSRYVLTAGHCLASRELDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRIC--AP 223
              ...|||::|:..::|||.||. .:.||.|          .|..|.         |..|.  :|
Mouse   225 --QHVCGGSILDPHWILTAAHCF-RKYLDVS----------SWKVRA---------GSNILGNSP 267

  Fly   224 KHIDIEVEKGIIHEMYAPNSV-DQRNDIALVRLKRIVSYTDYVRPICLPTDGLVQNNFVDYGMD- 286
               .:.|.|..|.|   ||.: .:..|||||:|:..::::..|||||||        |.|..:.
Mouse   268 ---SLPVAKIFIAE---PNPLYPKEKDIALVKLQMPLTFSGSVRPICLP--------FSDEVLVP 318

  Fly   287 -----VAGWGLTENM--QPSAIKLKITVNVWNLTSCQEKYSSFKVKLDDSQMCAG-GQLGVDTCG 343
                 |.|||.||..  :.|.:.|:.:|.|.:.|.|..: .:::.::....:||| .|.|.|||.
Mouse   319 ATPVWVIGWGFTEENGGKMSDMLLQASVQVIDSTRCNAE-DAYEGEVTAEMLCAGTPQGGKDTCQ 382

  Fly   344 GDSGGPLMVPISTGGRDVFYIAGVTSYGTKPCGLKGWPGVYTRTGAFIDWI 394
            ||||||||.     ..|.:.:.|:.|:| ..||....|||||:..|:::||
Mouse   383 GDSGGPLMY-----HSDKWQVVGIVSWG-HGCGGPSTPGVYTKVTAYLNWI 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPE	NP_651168.1	CLIP	36..94	CDD:463440	16/76 (21%)
		Tryp_SPc	135..397	CDD:238113	88/272 (32%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060	7/33 (21%)
		SRCR_2	106..195	CDD:470597	16/91 (18%)
		Tryp_SPc	202..427	CDD:214473	87/271 (32%)