DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPE and try-6

DIOPT Version :9

Sequence 1:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_001361988.1	Gene:	try-6 / 185959	WormBaseID:	WBGene00006624	Length:	343	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	72/310 - (23%)
Similarity:	119/310 - (38%)	Gaps:	62/310 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 CGFLFADRIFGGTNTTLWEFPWMVLLQ-YK--KLFSETYTFNCGGALLNSRYVLTAGHCLAS-RE 187
            ||.....:||.|....:.|.||.|.:. |.  |...||::.:|.|.|.:.|::|||.||.|: .|
Worm    33 CGKNVKSKIFNGRKAEIDEAPWAVRINTYTNVKNIDETWSKHCSGTLTSPRHILTATHCAATYTE 97

  Fly   188 LDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICA--PKHIDIEVEKGIIHEMYAPNSVDQR--- 247
            .:.:|.|:.:....::..........::...||..  ....:|...|.:....|....||:.
Worm    98 TEWNGTVIDAPIYRKYCEEQSTLIVREVAASRIVVRLRNRTEIGRAKYLFMFNYCRKIVDKNAYE 162

  Fly   248 ----NDIALVRLKRIVSYTDYVRPICLPTDGLVQNNFVDYGMDVAGWG-LTENMQPSAIKLKITV 307
                :||.::.|...|.|:..::|:|:.  |...:|..:..:|:.|:| .....:||::|
Worm   163 IQYPDDIMIIELSEDVEYSSELKPVCVA--GNTDDNAPNSHLDLFGFGDDPPRDKPSSLK----- 220

  Fly   308 NVWNLTSCQEKYSSFKVKLDDSQMCAGGQLGVD--------------TCGGDSGG---------P 349
               ||.....|:  .||::.|... .|....:|              .|.||||.         .
Worm   221 ---NLHDIPLKH--HKVEIMDMNK-EGTSKRMDPRLFIAKSVTRTSVACPGDSGAGGVKEIDKRT 279

  Fly   350 LMVPIST---------GGRDVFYIAGVTSYGTKPCGLKGWPGVYTRTGAF 390
            .:|.:.|         ..||....|....|....|   .:.|:.|.:|:|
Worm   280 TVVGVFTKTTCKFVYRDKRDEETYASFGFYANDVC---EYTGICTTSGSF 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPE	NP_651168.1	CLIP	42..94	CDD:314844
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	70/302 (23%)
try-6	NP_001361988.1	DUF316	7..320	CDD:367641	69/302 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12390
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860