DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SPE and try-4

DIOPT Version :9

Sequence 1:NP_651168.1 Gene:SPE / 42791 FlyBaseID:FBgn0039102 Length:400 Species:Drosophila melanogaster
Sequence 2:NP_508030.4 Gene:try-4 / 185148 WormBaseID:WBGene00006622 Length:324 Species:Caenorhabditis elegans


Alignment Length:273 Identity:62/273 - (22%)
Similarity:105/273 - (38%) Gaps:75/273 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 FPWMVLLQYKKLFSETYTFNCGGALLNSRYVLTAGH------------CLASRELDKSGAVLHSV 198
            |||.|      .|:.......||::::..:::||.|            |........:.::..|:
 Worm    58 FPWAV------SFTVDGVNRLGGSIISPYHIITAAHGFITTIGSRGNLCENKNWKKPNSSIYRSI 116

  Fly   199 RLGEWDTR-----------------TDPDCTTQMNGQRICAPKHIDI---EVEKGIIHEMYAPNS 243
            :... |||                 .||.|            |..|:   :|...::...:|.::
 Worm   117 KFLR-DTRKVAYGGTCIRGHTDKYPNDPRC------------KKSDVIHNKVRAVLVDGEFASSN 168

  Fly   244 VDQRNDIALVRLKRIVSYTDYVRPICLPTDGLVQNNFVDYGMDVAGWGLTENMQPSA-----IKL 303
            ..:.:|.|:|.:::.:.:::.|||||||.    .|.:....:.|.|||.:.....|.     |.:
 Worm   169 CLKGHDWAIVEVEKRIHFSENVRPICLPR----PNMYYTKSLAVPGWGRSYIFNESGPLIHEIPM 229

  Fly   304 KITVNVWNLTSCQEKYSSFKVKLDDSQMCAGGQLGVD------TCGGDSGGPLMVPISTGGRDVF 362
            :|.      ..|:..:|. ::..|.........:.|.      ||.|||||.|.......|| .|
 Worm   230 RID------RDCKRPWSD-RLPADADDFICATSMNVSNYSAPRTCHGDSGGGLEYRDDNYGR-AF 286

  Fly   363 YIAGVTSYGTKPC 375
            .|| :||:||:.|
 Worm   287 LIA-ITSFGTRGC 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SPENP_651168.1 CLIP 42..94 CDD:314844
Tryp_SPc 135..397 CDD:238113 62/273 (23%)
try-4NP_508030.4 Tryp_SPc 51..318 CDD:238113 62/273 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24260
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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