DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPE and LOC100004411

DIOPT Version :9

Sequence 1:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	404	Identity:	119/404 - (29%)
Similarity:	179/404 - (44%)	Gaps:	81/404 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SCTPQQSD---ERGQCVHITS--------CPYLANLLMVEPK---TPAQRILLSKSQCGLDNRVE 84
            :|..:.||   :.|.|:|..|        |.......:.|.:   :||.:....|...|
Zfish   120 NCETEVSDCKYKNGGCLHYCSQNETAGVECSCADGYQLDEDRHSCSPAVQYPCGKQWTG------ 178

  Fly    85 GLVNRIL--VCCPQSMRGNIMDSEPTPS-----TRDALQQG-----------DVL--PGNDVCGF 129
            |:::|.|  |....:...|...|..:||     .|.||:..           |.|  .|:|..|.
Zfish   179 GIMSRSLDDVSHTHADYANHTHSSTSPSHPLHHNRSALENSTHQNQTELTAPDQLLDTGSDFTGG 243

  Fly   130 LFADRIFGGTNTTLWEFPWMVLLQYKKLFSETYTFNCGGALLNSRYVLTAGHCLASRELDKSGAV 194
            ....||.||........||.|||:.:    :.|.| |||:|:|.|:|:||.|||....
Zfish   244 NEDTRIVGGQLQRQGGSPWQVLLRRE----DEYGF-CGGSLINQRWVITAAHCLQQTP------- 296

  Fly   195 LHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEVEKGIIHEMYAPNSVDQRNDIALVRLKRIV 259
             |.:.:|::| :..||...|            .|.|||.|.|..|...:.|  :||||:.|...|
Zfish   297 -HHITIGDYD-KMRPDKDEQ------------KITVEKIIPHPHYHEYTFD--SDIALLYLSSAV 345

  Fly   260 SYTDYVRPICLPTDGLVQNNFV--DYGMDVAGWGLTENMQPSAIKL-KITVNVWNLTSCQEKYSS 321
            :...:..|.|||...|.:....  :.|: |:|||.|..:|.|:..| |:.:.|....||   .:|
Zfish   346 TLGPFASPACLPDANLAERLMKPGEQGL-VSGWGSTHYLQRSSRFLRKVQLPVVEQKSC---INS 406

  Fly   322 FKVKLDDSQMCAGGQL-GVDTCGGDSGGPLMVPISTGGRDVFYIAGVTSYGTKPCGLKGWPGVYT 385
            .:..:.|:..|||..: .:|.|.||||||.:|    ..|..:::.||.|:|.: |..:|..||||
Zfish   407 TEQIITDNMFCAGFLMEEMDACTGDSGGPFIV----NYRGTWFLTGVVSWGER-CASQGKYGVYT 466

  Fly   386 RTGAFIDWIKQKLE 399
            |.|.::.||:::::
Zfish   467 RLGNYLSWIQEEMK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPE	NP_651168.1	CLIP	42..94	CDD:314844	14/64 (22%)
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	89/265 (34%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011	0/1 (0%)
		FXa_inhibition	128..164	CDD:291342	6/35 (17%)
		Tryp_SPc	248..475	CDD:214473	88/263 (33%)
		Tryp_SPc	249..477	CDD:238113	89/264 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920