DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF3d1 and AT5G44320

DIOPT Version :9

Sequence 1:	NP_524463.2	Gene:	eIF3d1 / 42789	FlyBaseID:	FBgn0040227	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_199245.1	Gene:	AT5G44320 / 834457	AraportID:	AT5G44320	Length:	588	Species:	Arabidopsis thaliana

Alignment Length:	576	Identity:	233/576 - (40%)
Similarity:	338/576 - (58%)	Gaps:	57/576 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FPSFEKPTVQFNEKGWGPCELPDT----------FKDVPYQPFSKNDRLGKICDWTNTSNNDKKY 65
            |.:||..||.||..||||.:..||          ..:||:..||::::||::.|||...:|....
plant     3 FEAFEVGTVPFNSDGWGPPDASDTSSTSVAAANLLPNVPFASFSRSEKLGRVADWTRALSNPSAR 67

  Fly    66 Q--------------NKYASSFGTGIQYSYYHEEDETTFHLVDTARVQKPPHQ-----RGRFRNM 111
            .              :.:|...|.|:..|..:.:::..|.|||    .|||.:     :.||...
plant    68 PHTGSKSDPSAIFDFSAFAVDEGFGLTNSGGNADEDAAFRLVD----GKPPPRPKFGPKWRFNQY 128

  Fly   112 RNSRSGRGRNARGGLNTHGMTTLSGKNVKARDPRHGRGMGKKFGHRGPPPKMRE-----SSVAVR 171
            .|         |..|.......:..|..:|...|..|.............:.||     |||.::
plant   129 HN---------RNQLPQRRDEEVEAKKREAEKDRARRDRLYNNNRNNIHQQRREAAAFKSSVDIQ 184

  Fly   172 ADWASIEEMDFPRLIKLSLPNIKEGVDIVTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTT 236
            .:|..:|::.|....|||. .:.|..|::.||.||.||:::|||..|.::.|::.......|||:
plant   185 PEWNMLEQIPFSTFSKLSF-TVSEPEDLLLCGGLESYDRSFDRITPKADRRLERFKNRSFKVTTS 248

  Fly   237 DDPVIRRLSK-TVGNVFATDAILATIMCSTRSNYSWDIVIEKVGDKVFMDKRDHTEFDLLTVNES 300
            ||.|||||:| ....|||||||||.:||:.||.||||:||::||:|:|.||||.:..|||:|:|:
plant   249 DDLVIRRLAKEDKATVFATDAILAALMCAPRSVYSWDLVIQRVGNKLFFDKRDGSPLDLLSVHET 313

  Fly   301 SVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVL-KTGDQEPKYKFEESNPFISEDEDIQVASVG 364
            |.||..:.....||..:|.:||.:||.||:|||| |.|.:|   .|:|..|.::|.|  :.||:.
plant   314 SQEPLPEGKDDINSAHSLGLEAAYINQNFAQQVLVKNGKRE---TFDEPIPNVNEGE--ENASIA 373

  Fly   365 YRYKKWELGSDIVLVARCEHDGVLQTPSGEPQFMTIKALNEWDSKLANGVEWRQKLDTQRGAVLA 429
            |||::|:|...:.||||||....:.. :.:..|:|:.||||:|.|. :||:|||||:||||||||
plant   374 YRYRRWKLDDSMYLVARCELQSTVDL-NNQRSFLTLNALNEFDPKY-SGVDWRQKLETQRGAVLA 436

  Fly   430 NELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNA 494
            |||:||..||||||.||:||.:|.:|:|:|||::||||..||||....:||.:||.||||:.:|.
plant   437 NELKNNGNKLAKWTAQALLANADMMKIGFVSRVHPRDHFNHVILSVLGYKPKDFAGQINLNTNNM 501

  Fly   495 WGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDEGFQ 550
            |||::.|:||.||..:|||:::|||:||.:|:|::|.:.||:|..::...:||..|
plant   502 WGIVKSIVDLCMKLSEGKYVLVKDPSKPQVRIYEVPADAFDNDYVEEPLPEDEQVQ 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3d1	NP_524463.2	eIF-3_zeta	14..528	CDD:282888	224/549 (41%)
AT5G44320	NP_199245.1	eIF-3_zeta	6..535	CDD:398661	224/549 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	397	1.000	Domainoid score	I139
eggNOG	1	0.900	-	-		E1_KOG2479
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2782
Inparanoid	1	1.050	412	1.000	Inparanoid score	I450
OMA	1	1.010	-	-		QHG53861
OrthoDB	1	1.010	-	-		D1030308at2759
OrthoFinder	1	1.000	-	-		FOG0004086
OrthoInspector	1	1.000	-	-		mtm989
orthoMCL	1	0.900	-	-		OOG6_102252
Panther	1	1.100	-	-	LDO	PTHR12399
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2834
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840