Protein Alignment eIF3d1 and eif3d

DIOPT Version :9

• Sequence 1: NP_524463.2
• Gene: eIF3d1 / 42789
• FlyBaseID: FBgn0040227
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_989075.1
• Gene: eif3d / 394672
• XenbaseID: XB-GENE-942853
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 544
• Identity: 317/544 - (58%)
• Similarity: 403/544 - (74%)
• Gaps: 14/544 - (2%)

  Fly    14 FEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTNTSNNDKKYQNKYASSFGTGIQ 78
            |:.|.:..|..|||||.:||.|||:|||||||.|||||:.|||..:..||:|.|||:|.||.|.|
 Frog     4 FQAPVINDNPLGWGPCAVPDQFKDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQ 68

  Fly    79 YSYYHEEDETTFHLVDTARVQKPPHQRGRFR-NMRNSRSGRGRNARGGLNTHGMTTLSGKNVKAR 142
            |:|:|:||||:|.||||.::||..:||.|.| ..||.|  |.::.|..|..:..|.......|.|
 Frog    69 YAYFHDEDETSFQLVDTTKMQKTAYQRNRLRFAQRNLR--RDKDRRNMLQFNMQTLPKSAKQKER 131

  Fly   143 DP-RHGRGMGKKFGHR-------GPPPKMRESSVAVRADWASIEEMDFPRLIKLSLPNIKEGVDI 199
            |. |..:...|:||.|       ....|.|:|||.||:||...||||||||:|:....:.:.:||
 Frog   132 DRLRLQKKFQKQFGVRQKWDQKSQAQLKPRDSSVEVRSDWEVKEEMDFPRLMKMRYMEVSDPLDI 196

  Fly   200 VTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTVGNVFATDAILATIMCS 264
            ..||.||:|||.:|||..:||:||:.|.||.||||||||||||:|:||.||||||||||||:||.
 Frog   197 ECCGALEFYDKAFDRITTRNERPLKSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMCC 261

  Fly   265 TRSNYSWDIVIEKVGDKVFMDKRDHTEFDLLTVNESSVEPPTDDDSSCNSPRNLAIEATFINHNF 329
            |||..|||||:::||.|:|.||||:::||||||:|::.|||.||.:|.|||||||:|||:|||||
 Frog   262 TRSVNSWDIVVQRVGSKIFFDKRDNSDFDLLTVSETANEPPQDDVNSLNSPRNLAMEATYINHNF 326

  Fly   330 SQQVLKTGDQEPKYKFEESNPFISEDED-IQVASVGYRYKKWELGSDIVLVARCEHDGVLQTPSG 393
            |||.|:.|.:  |:.|...||||.:|.| .:||||.|||::|:||.||.||.||||||.:...:|
 Frog   327 SQQCLRMGKE--KHTFPNPNPFIEDDVDKNEVASVAYRYRRWKLGDDIDLVVRCEHDGFMTGANG 389

  Fly   394 EPQFMTIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGY 458
            |..|:.||.||||||:..|||:||||||:|||||:|.||:||:.|||:||..|:||||:.|||||
 Frog   390 EVSFVNIKTLNEWDSRYCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGY 454

  Fly   459 VSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPI 523
            |||.:.:|.:|||:||||||||:|||.||||||:||||||||::|:.||..:|||||:|||||.:
 Frog   455 VSRCHVKDSTRHVVLGTQQFKPNEFANQINLSMENAWGILRCVVDICMKLDEGKYLILKDPNKQV 519

  Fly   524 IRLYDIPDNTFDSDDSDDGEGDDE 547
            ||:|.:||.||.||:.||.:.::|
 Frog   520 IRIYSLPDGTFSSDEEDDDDDEEE 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3d1	NP_524463.2	eIF-3_zeta	14..528	CDD:282888	307/523 (59%)
eif3d	NP_989075.1	eIF-3_zeta	4..524	CDD:368281	307/523 (59%)
		RNA gate. /evidence=ECO:0000250|UniProtKB:K7IM66	288..302		8/13 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..552		9/18 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	622	1.000	Domainoid score	I179
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2782
Inparanoid	1	1.050	647	1.000	Inparanoid score	I793
OMA	1	1.010	-	-		QHG53861
OrthoDB	1	1.010	-	-		D1030308at2759
OrthoFinder	1	1.000	-	-		FOG0004086
OrthoInspector	1	1.000	-	-		otm48258
Panther	1	1.100	-	-	LDO	PTHR12399
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R379
SonicParanoid	1	1.000	-	-		X2834
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110