DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31145 and fam20cb

DIOPT Version :9

Sequence 1:	NP_001356923.1	Gene:	CG31145 / 42784	FlyBaseID:	FBgn0051145	Length:	982	Species:	Drosophila melanogaster
Sequence 2:	XP_021335966.1	Gene:	fam20cb / 560397	ZFINID:	ZDB-GENE-050301-4	Length:	557	Species:	Danio rerio

Alignment Length:	380	Identity:	203/380 - (53%)
Similarity:	267/380 - (70%)	Gaps:	16/380 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   608 SRDN---PTLAEMLHRKASANASNLERFQLRITKKELYGEQDTLVDAVLRDMIKLPIQHVVQKEG 669
            |:|.   || .||    :|.:..|..||.:.|.:.|||...:.::||:|:|::...|..|..|.|
Zfish   177 SKDGDYAPT-GEM----SSDSYPNWLRFHIGINRYELYSRHNPVIDAMLKDLVSQRITSVAMKSG 236

  Fly   670 GTQLKLIIEYPNDIKALMKPMRFPREQQTLPNHFYFTDYERHNAEIAAFHLDRILGFRRAMPVAG 734
            |||||||:.:.|..:||.|||:..|||:|.|:.|||:|:|||||||||:||||||.|||..||||
Zfish   237 GTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAYHLDRILDFRRVPPVAG 301

  Fly   735 RTLNITTEIYQLA-EENLLKTFFVSPSLNLCFHGKCSYYCDTSHAICGNPDMLEGSFAAFLPNFE 798
            |.:|:|.||..:. ::.|.:|||:||:.|:||:|:|||||.|.||:||.||.:|||.|||||:..
Zfish   302 RLVNMTKEIRDVTRDKKLWRTFFISPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLS 366

  Fly   799 SGNRKLWRHPWRRSYHKRKKAQWETDANYCALVRDIPPYDDGRRLYDLMDMAVFDFLTGNMDRHH 863
            ...|:.||:||||||||||||:||.|.:||..|:..||||.|.||.|:|||.:||||.|||||||
Zfish   367 LAKRRTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSGTRLLDIMDMTIFDFLMGNMDRHH 431

  Fly   864 YETFKVYGNETFPLHLDHGRGFGRPFHDELSILAPVLQCCLIRKSTLVKLLDFHNGPKPLSQLMS 928
            ||||:.:|||||.:|||:|||||:..|||||||.|:.|||.::|||.::|.........||.||.
Zfish   432 YETFEKFGNETFIIHLDNGRGFGKHSHDELSILVPLSQCCRVKKSTHLRLQLVAKEEFKLSSLME 496

  Fly   929 ESLSQDPVSPVLWQPHLEALDRRTGIILQSIRDCIKRNPPGDV-------DGSET 976
            |||..|.:||:|.:|||||:|||..::||.:.|||::....:|       :|.:|
Zfish   497 ESLQTDTLSPILIRPHLEAMDRRLRLVLQVLADCIEKEGYSNVVEDDMGTEGMDT 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31145	NP_001356923.1	Fam20C	755..971	CDD:336477	127/215 (59%)
fam20cb	XP_021335966.1	FAM20_C_like	324..535	CDD:323276	126/210 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581824
Domainoid	1	1.000	291	1.000	Domainoid score	I1496
eggNOG	1	0.900	-	-		E1_KOG3829
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227822at33208
OrthoFinder	1	1.000	-	-		FOG0004028
OrthoInspector	1	1.000	-	-		otm24459
orthoMCL	1	0.900	-	-		OOG6_107364
Panther	1	1.100	-	-	O	PTHR12450
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4404
SonicParanoid	1	1.000	-	-		X1341
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.740