DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10184 and THA2

DIOPT Version :9

Sequence 1:	NP_651161.1	Gene:	CG10184 / 42783	FlyBaseID:	FBgn0039094	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001327633.1	Gene:	THA2 / 819608	AraportID:	AT3G04520	Length:	355	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	175/382 - (45%)
Similarity:	242/382 - (63%)	Gaps:	36/382 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TTHSVVDLRSDTVSQPTDKMRARMATAVVGDDVYGEDPTVNELEARTAAIFGKEAGLFVPSGTMG 66
            ||...||||||||::||:.||:.||.|.|.|||.|.|||...||...|.|.||||.:||||||||
plant     5 TTIRTVDLRSDTVTKPTESMRSAMANAEVDDDVLGNDPTALRLEKEVAEIAGKEAAMFVPSGTMG 69

  Fly    67 NLLAIMVHCHRRGTEALVGDLSHIFLYEQGGASHLAGVQLATLKNEQDGTFSLQDLRRRIRHE-- 129
            ||::::|||..||:|.::||.|||.:||.||.|.|.||...|:|||:|||..:..:...:|..
plant    70 NLISVLVHCDERGSEVILGDDSHIHIYENGGVSSLGGVHPRTVKNEEDGTMEIGAIEAAVRSPKG 134

  Fly   130 DCHEPITSLVVVEQTHNICGGKVVPLAFLDELAALVRQPGVGTGNARIALHMDGARVFNAATALG 194
            |.|.|:|.|:.:|.|...|||:.:|:.::|::..|.::.|       :.||:||||:|||:.|||
plant   135 DLHHPVTKLICLENTQANCGGRCLPIEYIDKVGELAKKHG-------LKLHIDGARIFNASVALG 192

  Fly   195 VGVERICRDFDSVSICLSKGLSAPVGSVLVGSKAFISEAHRLRKALGGGMRQVGVLAAAGLVALD 259
            |.|:||.:..||||||||||:.||||||:||||.||::|..|||.|||||||:|||.||.||||.
plant   193 VPVKRIVQAADSVSICLSKGIGAPVGSVIVGSKKFITKARWLRKTLGGGMRQIGVLCAAALVALH 257

  Fly   260 EVVPLLSKDHERTNKIANAIYELKSPNITVHVSSVQSNILLVEITQ-PKLTASEFSTRLSIVDAG 323
            |.|..|..||::...:|..:..::  .:.|:|::|::||:.|:|.: ||..|.|....|..|
plant   258 ENVAKLEDDHKKARVLAEGLNRIE--RLRVNVAAVETNIIYVDIPEDPKFGAEEACKSLEDV--- 317

  Fly   324 EVEAGVKDKNGAGIVVKASARDWAFARLVLYHQVDDEQVDLAIRKLKYVIGQYDKQF 380
                      |..::.:|:.|    .|:||:||:.|..|:       ||:..::|.|
plant   318 ----------GVLVIPQATFR----IRIVLHHQISDVDVE-------YVLSCFEKIF 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10184	NP_651161.1	AAT_I	6..366	CDD:302748	169/362 (47%)
THA2	NP_001327633.1	PLN02721	3..355	CDD:178323	175/382 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	295	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E1_COG2008
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57081
Inparanoid	1	1.050	313	1.000	Inparanoid score	I732
OMA	1	1.010	-	-		QHG61665
OrthoDB	1	1.010	-	-		D1099858at2759
OrthoFinder	1	1.000	-	-		FOG0003347
OrthoInspector	1	1.000	-	-		otm3370
orthoMCL	1	0.900	-	-		OOG6_102336
Panther	1	1.100	-	-	LDO	PTHR48097
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2233
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840