DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10184 and R102.4

DIOPT Version :9

Sequence 1:	NP_651161.1	Gene:	CG10184 / 42783	FlyBaseID:	FBgn0039094	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_501979.3	Gene:	R102.4 / 177961	WormBaseID:	WBGene00011291	Length:	413	Species:	Caenorhabditis elegans

Alignment Length:	380	Identity:	159/380 - (41%)
Similarity:	215/380 - (56%)	Gaps:	37/380 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 THSVVDLRSDTVSQPTDKMRARMATAVVGDDVYGEDPTVNELEARTAAIFGKEAGLFVPSGTMGN 67
            ||:.:|||||||:.|:.:||..||.|:|||||||||.|.|.||.|.|.:|||||||||.||||||
Worm    63 THTSIDLRSDTVTVPSVEMRRAMAEAIVGDDVYGEDTTTNRLEQRCAELFGKEAGLFVTSGTMGN 127

  Fly    68 LLAIMVHCHRRGTEALVGDLSHIFLYEQGGASHLAGVQLATLKNEQDGTFSLQDLRRRIRHEDCH 132
            |||||.|| :||.|.:||..:||..:|||..:..||:...||:.:.|||..|.|:.:.||.:|||
Worm   128 LLAIMAHC-QRGEEIIVGRYNHIHRWEQGNYAQFAGISATTLEVKPDGTMDLNDIEQAIRVKDCH 191

  Fly   133 EPITSLVVVEQTHNICGGKVVPLAFLDELAALVRQPGVGTGNARIALHMDGARVFNAATALGVGV 197
            .|.:.|:.:|.|||..|||.:|:.::..:..|..:       ..:.:||||||::|||.|....|
Worm   192 MPASKLICIENTHNYTGGKALPIEWMRSVKQLAER-------RDLKVHMDGARIYNAAVASNCSV 249

  Fly   198 ERICRDFDSVSICLSKGLSAPVGSVLVGSKAFISEAHRLRKALGGGMRQVGVLAAAGLVALDEVV 262
            .:|....|:|.:|.||||.|||||::||.|.||..|...|||||||.||.|:||||..:|||...
Worm   250 SKIASFADTVQMCFSKGLGAPVGSIVVGPKDFIDRARHSRKALGGGWRQSGILAAAAHIALDHAD 314

  Fly   263 PLLSKDHERTNKIANAIYELKSPNITVHVSSVQ---SNILLVE----ITQPKLTASEFSTRLSIV 320
            ..:..||||...:|..|.:.........|.:.:   :|::||.    :|..:||  :|..:..|:
Worm   315 ATIRADHERAKTLARMINDATPEEFRTKVFAAEKDITNMVLVHCQNGVTVQQLT--DFFQKHDIL 377

  Fly   321 DAGEVEAGVKDKNGAGIVVKASARDWAFARLVLYHQVDDEQVDLAIRKLKYVIGQ 375
                                |...|....|:||...|.||.::..:...|..:.|
Worm   378 --------------------AMTFDARRIRMVLNWNVSDENLETIVEVYKKFLKQ 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10184	NP_651161.1	AAT_I	6..366	CDD:302748	155/366 (42%)
R102.4	NP_501979.3	Beta_elim_lyase	68..357	CDD:366516	141/296 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167051
Domainoid	1	1.000	267	1.000	Domainoid score	I994
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57081
Inparanoid	1	1.050	274	1.000	Inparanoid score	I1798
Isobase	1	0.950	-	0	Normalized mean entropy	S2246
OMA	1	1.010	-	-		QHG61665
OrthoDB	1	1.010	-	-		D1099858at2759
OrthoFinder	1	1.000	-	-		FOG0003347
OrthoInspector	1	1.000	-	-		oto18601
orthoMCL	1	0.900	-	-		OOG6_102336
Panther	1	1.100	-	-	LDO	PTHR48097
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R501
SonicParanoid	1	1.000	-	-		X2233
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890