DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10182 and CG17707

DIOPT Version :9

Sequence 1:	NP_651158.1	Gene:	CG10182 / 42780	FlyBaseID:	FBgn0039091	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_001162627.1	Gene:	CG17707 / 5740408	FlyBaseID:	FBgn0025835	Length:	990	Species:	Drosophila melanogaster

Alignment Length:	786	Identity:	176/786 - (22%)
Similarity:	289/786 - (36%)	Gaps:	214/786 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 VSQLKGLA--LDFVGQVKDFDVEELSTLETRVPSQEDMLCLSDLTALTTGLQSGQYWALKMFDSW 95
            |..|.|.|  ...|..:.|....::|.:.|.|.:.    |..::.|..|.|.|...||.|.:||.
  Fly   244 VESLYGQANYFQLVANLYDHFYWQISEIRTNVHTG----CGLEMQAYLTALHSSYEWAQKAYDSS 304

  Fly    96 GSIPSGLLTGNMYDLGNFDECLNIN----------------------HGVSLGRTIQGKYCFLSV 138
            |.....||.||...||....|..:|                      |..||.|
  Fly   305 GRYRGQLLFGNDKWLGQLSFCYELNRQSLTEERQHFDLQFYVADVALHLPSLNR----------- 358

  Fly   139 SLAQALGVQSSIIGHFKTATCLPASCS----------------ATYM---NTFMGMVTKQLLNV- 183
            |:..:||            .|||.|||                .|.:   ||.|.....|:|:|
  Fly   359 SMLLSLG------------ECLPKSCSDIDVKSILSLDPYARMLTVLGAHNTSMQQPPLQILHVR 411

  Fly   184 SIPSSVMSISESSCQTSESVPWDGLTIFMIVILS------------VMGSLVAL----------- 225
            ::|.......:...|...|..   ||:|::::::            |:..:.|:
  Fly   412 TVPGIYSHWRQLKFQVFISFM---LTLFLVILVASYYQLKIDERRLVVAPIAAISGKCDGTSTKN 473

  Fly   226 -------FTLWDY----CLGKNQD----------------------------------------- 238
                   |.|:..    |...:.|
  Fly   474 DVFYGKSFELFQMRPLGCTSSSTDDPEVDVNGNRQRCGDSSDMENGVQREFADPNTSTSVGEKSE 538

  Fly   239 ----QLPT---------------------IVKVFSARVNSRALFRIVEVNSSPNV-IDCLHGIRC 277
                |:.|                     |:..|:.:.|::|   |:.:|.:..: ..||||:|.
  Fly   539 MGDYQMETGSCAGGTGTYEAKQSVALHQQILLCFALQTNAKA---ILNINKTKEIHTACLHGLRV 600

  Fly   278 LSLMWVVFCHQYV-MAALASNINIFHAISWEETPYASFILHGFFSVDSFFVLGGLLVALIPLRMM 341
            .|::|.:..|.|: |.|:..  |.|..|..|.:.:...|.:..|||||||.:.||||.::.|:..
  Fly   601 FSVLWTMMVHTYLQMFAIGE--NKFERIITERSFWYQVIGNATFSVDSFFFISGLLVTMLYLKQN 663

  Fly   342 DR--TKGKLNVP-------LMYLHRLIRIVPLLAIAIVMYLKLMPIVADGPRFGSGYSGTVDCEN 397
            .:  |:..|.:.       :|.|:|.:|:.|:....::.....:....|...|.........|..
  Fly   664 RKYPTETCLFIKSCFSESLMMLLYRYLRLTPVYLFVVIFNDFAVRQGLDTSVFQPAKIEHNTCRM 728

  Fly   398 GWYWTLLFVNNY--TEEKCLGHTWYLSVDMQLFILSPIMLIALYKWGKKAAAGIFVLIV---LLS 457
            .|:..:|::|||  ..|.|:..:||::.:||.::::.::|....|:.|..|..:||.::   .:|
  Fly   729 YWWRNILYINNYFPQTEMCMMWSWYMANEMQFYVMAALLLALARKYFKAVAITLFVFLLSSWSIS 793

  Fly   458 GCLFATIM-VNKYSLVLKNFSMDAQKDLYFATHTHATPWLTGFLFGYSLHLNRGKKFQLSKVVAW 521
            |.:..|.. .:|.||..::|..     ||.........::.|...||.|:..:.... :|:.:..
  Fly   794 GIISLTYQYTHKVSLPFESFDF-----LYDKPWQRVGSYIMGMCTGYVLYKVKTPPL-ISRRLNL 852

  Fly   522 SGWILCLAMIFTSIFALYPYAKWTGPDLSTFAEASYYTLTRVGWCMALCWVIFACMNGYGGLANS 586
            |.|...|.::...:|.:     |.| .|.|.:.|.|..:....:...|.|::.:|..|.....|:
  Fly   853 SLWACSLFVLLIVVFGV-----WEG-HLGTTSSAFYVGVAHTAFGCGLVWIVLSCCWGLVPTVNA 911

  Fly   587 FLSSPLWQPLSRLSYSVYMWHMFFQEINIRSMRTNSYFSNYTIMLNFWSTFGFAVL---FAYVMH 648
            .||..:..|||||:|..|:.|.....|....|....:.||..|:..|   .|.||:   .|:|:.
  Fly   912 ILSYRVMWPLSRLTYCAYLIHPIIMFICSSHMSGTVHLSNPLILTLF---LGNAVVSFGCAFVIS 973

  Fly   649 LVIEAP 654
            ...|||
  Fly   974 AFFEAP 979

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10182	NP_651158.1	NRF	85..186	CDD:214781	34/142 (24%)
		Acyl_transf_3	269..645	CDD:280013	103/394 (26%)
		OafA	300..655	CDD:224748	96/373 (26%)
CG17707	NP_001162627.1	NRF	294..399	CDD:214781	29/127 (23%)
		Acyl_transf_3	595..973	CDD:280013	104/394 (26%)
		OafA	597..985	CDD:224748	105/400 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	6	5.920