DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10182 and drd

DIOPT Version :9

Sequence 1:	NP_651158.1	Gene:	CG10182 / 42780	FlyBaseID:	FBgn0039091	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_001033845.1	Gene:	drd / 318102	FlyBaseID:	FBgn0260006	Length:	827	Species:	Drosophila melanogaster

Alignment Length:	763	Identity:	193/763 - (25%)
Similarity:	329/763 - (43%)	Gaps:	154/763 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 NDEDVLSDLQRVSQLKGLALDFVGQVKDFDVEELSTLETRVPSQEDMLCLSDLTALTTGLQSGQY 86
            :|:|.:.:.:| :.|..:...|:...:.||........|        ||...:......|.:...
  Fly   115 DDDDQVEEDER-AYLYNIGKRFLAITQPFDAARNPDAST--------LCRRQMHQFLNALDNFDL 170

  Fly    87 WALKMFDSWGSIPSGLLTGNMYDLGNFDECLNI----NHGVSLGR------TIQGKYCFLSVSLA 141
            |||||.||.|.:.||:|.||:...|:||:||.|    |.....|:      .|:|:||   ::.|
  Fly   171 WALKMHDSSGKLNSGILNGNINQPGDFDQCLGIQQRMNQDQDAGQDQDGDSIIRGQYC---LAYA 232

  Fly   142 QALGVQSS--------II---GHFKT-----------------ATCLPASCSATYMN----TFMG 174
            |.:...:|        :|   |.||:                 ..|:|:.|||..:.    .::|
  Fly   233 QPVLPHNSKRLKSFFKLIQSHGPFKSEFNDPGHRVPRYSLINWGLCVPSGCSARDVEYSVAEYLG 297

  Fly   175 MVTKQLLNVSIPSSVMSISESSCQTSESVPWDGLTIFMIVILSVMGSLVALFTLWDYCLGKNQDQ 239
               .|..:..|..:| .:....||..:..|||..|.:.:....::.|:..|.|::|........|
  Fly   298 ---NQTASTGITFNV-RVEPQMCQVRDQRPWDRNTTWAVRFFLLVLSVAVLSTIYDRSTKSQPKQ 358

  Fly   240 LPTIVKVFSARVNSRALFRIVEVNSSPNVIDCLHGIRCLSLMWVVFCHQYV---------MAALA 295
            .|... .||...|.|.||   ..:|:|..|:.:||||.|:.:.::|.|:.:         ..|::
  Fly   359 NPWFT-AFSLDKNLRWLF---STSSAPGDIEAVHGIRFLNAIMLIFSHKSMAMFFNPYNNRTAMS 419

  Fly   296 SNIN-----IFHAISWEETPYASFILHGFFSVDSFFVLGGLLVALIPLRMMDRTKGKLNVPLMYL 355
            .::.     |..|.|....|:..|  .|..:..|.|   |.|:...|:|:.:.          |:
  Fly   420 ESLGQPWTVIGRAASLYTDPFLLF--SGMLTSYSLF---GRLMKQQPIRLKNE----------YI 469

  Fly   356 HRLIRIVPLLAIAIVMYLKLMPIVADGPRFG--SGYSGTVDCENGWYWTLLFVNNY--TEEKCLG 416
            .||:||||.||..|:....::|:...||::.  .|:...: |:..|:..|||::||  ..|.||.
  Fly   470 SRLMRIVPPLAALILFCTYVLPLWGSGPQWNLVVGHHADI-CKKNWWRNLLFIHNYFGFSEMCLT 533

  Fly   417 HTWYLSVDMQLFILSPIMLIALYKWGKKAAAGIFVLIVLL---SGCLFATIMVNKYSLVLKNFSM 478
            ||.:|.:|.:||.::|::::||::|.::   |:|.|::|.   :...:.|.:||:    |.|:
  Fly   534 HTHHLGIDTELFAVAPLLILALWRWPRR---GLFALLLLCTVGTAARYYTTIVNQ----LSNY-- 589

  Fly   479 DAQKDLYFATHT----------------HATPWLTGFLFGYSLHLNRGKKFQ---LSKVVAWSGW 524
                 :||.|:.                .:|.::.|.|.||.|     :|:|   ||.:....||
  Fly   590 -----IYFGTNIQRLFRTADYMYSFPPHRSTVYIMGILLGYVL-----RKYQNARLSSLQLRLGW 644

  Fly   525 ILCLAMIFTSIFALYPYAKWTGPDLSTFAEASYYTLTRVGWCMALCWVIFACMNGYGGLANSFLS 589
            ::....:..|:....|.........||.| |.|.....:.||:...|::|...|||........:
  Fly   645 LVATVCVLASLLGPAPMGDINYVYNSTHA-AIYAAFAPIAWCLFFSWIVFVSHNGYTNKLTKLFA 708

  Fly   590 SPLWQPLSRLSYSVYM--WHMFFQEINIRSMRTNSYFSNYTIMLN---FWSTFGFAVLFAYVMHL 649
            ...:|..::|||::|:  :.:||..:. |....:.|::..:|:|:   |.|.|    |.:..:.:
  Fly   709 WRGFQVSTKLSYAIYLTQFPVFFFNVG-RRRHIHHYYNFVSIILDTNEFISIF----LASVALTV 768

  Fly   650 VIEAPFGGLDYFLRPKQKTPPLVKQKSQIDDNGHNNLEELKVTTPTPA 697
            :.:|||..|...|..:.....:||      |:.....|....||.|.|
  Fly   769 LFDAPFQNLKKLLIKRPTAAKVVK------DSKAKAAESQDATTTTLA 810

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10182	NP_651158.1	NRF	85..186	CDD:214781	39/142 (27%)
		Acyl_transf_3	269..645	CDD:280013	108/420 (26%)
		OafA	300..655	CDD:224748	100/385 (26%)
drd	NP_001033845.1	NRF	169..>289	CDD:214781	37/122 (30%)
		OafA	371..791	CDD:224748	118/463 (25%)
		Acyl_transf_3	384..770	CDD:280013	108/426 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920