DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10182 and CG33337

DIOPT Version :9

Sequence 1:	NP_651158.1	Gene:	CG10182 / 42780	FlyBaseID:	FBgn0039091	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster

Alignment Length:	701	Identity:	412/701 - (58%)
Similarity:	518/701 - (73%)	Gaps:	18/701 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVNIVGVVFLCGLGLISAGRLNDEDVLSDLQRVSQLKGLALDFVGQVKDFDVEELSTLETRVPSQ 65
            ||.|:..:.|.||.||.|.:..|..||.:.||:.:||.|.::|....::..:.:||..::|:|:|
  Fly     1 MVKILSFILLSGLVLIGAIQSEDRSVLEEYQRLRKLKPLGIEFADYFQNVTLNDLSLFDSRLPTQ 65

  Fly    66 EDMLCLSDLTALTTGLQSGQYWALKMFDSWGSIPSGLLTGNMYDLGNFDECLNINHGVSLGRTIQ 130
            .|:|||:|||.|.:.||.|||||.||.|:||.||||:.|||:|||||||||:||...     :|:
  Fly    66 ADLLCLNDLTKLVSALQGGQYWAFKMIDAWGGIPSGIFTGNVYDLGNFDECINIKKD-----SIR 125

  Fly   131 GKYCFLSVSLAQALGVQSSIIG--HFKTATCLPASCSATYMNTFMGMVTKQLLNVSIPSSVMSIS 193
            ||||||.||.|:.|||:||:.|  ..|||||.|||||||:||.|:..:.|::|||||||:.||||
  Fly   126 GKYCFLDVSPAKILGVESSLAGILKIKTATCFPASCSATHMNKFVDTILKRILNVSIPSTAMSIS 190

  Fly   194 ESSCQTSESVPWDGLTIFMIVILSVMGSLVALFTLWDYCLGKNQDQLPTIVKVFSARVNSRALFR 258
            :.||||:||.||.||||..|||||:||.:||:.||:||.|.|:||||.|.||:||||.||.||||
  Fly   191 DDSCQTAESEPWSGLTILTIVILSLMGVIVAIATLYDYFLVKSQDQLHTAVKLFSARANSCALFR 255

  Fly   259 IVEVNSSPNVIDCLHGIRCLSLMWVVFCHQYVMAALASNINIFHAISWEETPYASFILHGFFSVD 323
            ||...|:||||:|||||||:||.|||:.|||.....|.|||.|..:||.:||:..|.|.|.||||
  Fly   256 IVVNQSNPNVIECLHGIRCMSLFWVVWIHQYDNVFSAPNINRFRFLSWLQTPFTMFFLEGNFSVD 320

  Fly   324 SFFVLGGLLVALIPLRMMDRTKGKLNVPLMYLHRLIRIVPLLAIAIVMYLKLMPIVADGPRFGSG 388
            |||.:||.||:|..|..|::..||:|||.||:.|.|||.|:||::|::|.:|..::.|||.|..|
  Fly   321 SFFFIGGFLVSLNALGTMEKNNGKINVPRMYIRRFIRIFPILAMSILVYTQLTGVLGDGPLFKGG 385

  Fly   389 YSGTVDCENGWYWTLLFVNNYTEEKCLGHTWYLSVDMQLFILSPIMLIALYKWGKKAAAGIFVLI 453
            ||....|...||.|||||.|:..:.||.|||||:||||||::|||:|.|||||||||||.|.|||
  Fly   386 YSKKASCAKTWYMTLLFVVNFANDMCLDHTWYLAVDMQLFLISPILLFALYKWGKKAAAAIGVLI 450

  Fly   454 VLLSGCLFATIMVNKYSLVLKNFSMDAQKDLYFATHTHATPWLTGFLFGYSLHLNRGKKFQLSKV 518
            ||||||||||:|||.||:...:||:  ||..||.|||||.|||.|||:||.:.||:|:||:::.:
  Fly   451 VLLSGCLFATMMVNHYSIKSLDFSL--QKKTYFYTHTHAAPWLIGFLYGYFVFLNKGRKFKMNWI 513

  Fly   519 VAWSGWILCLAMIFTSIFALYPYAKWTGPDLSTFAE-ASYYTLTRVGWCMALCWVIFACMNGYGG 582
            ..||||||||||:|||||||||..:...|.|.|..| :||||||||||.||:.||:||||.||||
  Fly   514 AVWSGWILCLAMLFTSIFALYPKLESGKPWLMTTLEVSSYYTLTRVGWPMAVGWVVFACMQGYGG 578

  Fly   583 LANSFLSSPLWQPLSRLSYSVYMWHMFFQEINIRSMRTNSYFSNYTIMLNFWSTFGFAVLFAYVM 647
            :||:|||||||||:|:||||:|:||.|.||||.|.:|||:|||||.:|||||||.||.|||:|::
  Fly   579 MANTFLSSPLWQPISKLSYSIYIWHSFIQEINKRIVRTNTYFSNYQVMLNFWSTMGFTVLFSYLL 643

  Fly   648 HLVIEAPFGGLDYFLRPKQKTP----PLVKQKSQIDDNGH----NNLEELK 690
            :|:||||.||||..||||:|.|    |:.......:.:||    :|..||:
  Fly   644 YLLIEAPIGGLDRLLRPKKKAPAENKPMTNSDRVGEGHGHDVDLSNQRELE 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10182	NP_651158.1	NRF	85..186	CDD:214781	63/102 (62%)
		Acyl_transf_3	269..645	CDD:280013	236/376 (63%)
		OafA	300..655	CDD:224748	221/355 (62%)
CG33337	NP_996269.2	NRF	85..196	CDD:214781	72/115 (63%)
		Acyl_transf_3	266..645	CDD:280013	237/380 (62%)
		OafA	300..666	CDD:224748	230/367 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458040
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	13	12.750