DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10182 and oac-32

DIOPT Version :9

Sequence 1:	NP_651158.1	Gene:	CG10182 / 42780	FlyBaseID:	FBgn0039091	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_001300114.1	Gene:	oac-32 / 186125	WormBaseID:	WBGene00018708	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	675	Identity:	184/675 - (27%)
Similarity:	299/675 - (44%)	Gaps:	118/675 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 WALKMFDSWGSIP-SGLL-TGNMYDLGNFDECLNINHGVSLGRTIQGKYCFLSVSLAQALGVQSS 149
            :|::..|::|..| :||| ...:|| |::.||..::     |:.....||:|  .|.....|.|.
Worm    79 YAVQQLDAFGQFPGAGLLELKTLYD-GSYQECQRVS-----GKKYDVNYCYL--LLTPGKNVSSC 135

  Fly   150 IIGHFKT---------ATCLPASCSATYMNTFMGMVTKQLLNVSIPSSVMSISESSCQTSESVPW 205
            ...:.|:         |.|||.||:...|......::      ..|.:..|...:..:..:..|:
Worm   136 APSNSKSLYSQLPLRIAVCLPDSCNHQDMIDIFNELS------PYPFTACSAYCTKNEVKKDTPF 194

  Fly   206 DGLTIFMI--VILSVMGSLVALF--TLWDYCLGKNQDQLPTIVKVFSARVNSRALFRIVEVNSS- 265
            .|.:||:|  |:::.:.|:|...  |::.....|..:....|:..||...|:..|..:.|..|.
Worm   195 WGFSIFLIVMVVIAAIASIVDYVRETVYGLSSQKENNTFFKILLTFSLWTNAELLLSVKEQKSGF 259

  Fly   266 PNVIDCLHGIRCLSLMWVVFCHQYVMAALASNIN---IFHAISWEETPYASFILHGFFSVDSFFV 327
            ...:||   ||.||:.|||..|.::...||..:.   .|....|..     .:|:.|.|||:|||
Worm   260 IKSLDC---IRLLSMCWVVTGHSFLYLILADTLEPVLDFPTYFWNH-----LLLNAFVSVDTFFV 316

  Fly   328 LGGLLVALIPLRMMDRTKGKLNVP----LMYLHRLIRIVPLLAIAIVMYLKLMPIVADGPRFGSG 388
            |.|::||.:..: ...||..:..|    |.|:||.:|:.|.:.:.|..:....|.:.      ..
Worm   317 LSGIVVAYLFFK-TKLTKKTITSPMTWILFYVHRYLRLTPPVMLFIGFFTVYTPYIQ------GA 374

  Fly   389 YSGT---------VDCENGWYWTLLFVNNYTE-----EKCLGHTWYLSVDMQLFILSPIMLIALY 439
            :|.:         ..|:..|:..||::||:.:     ..|.|.||||:||.||::::||:|:|||
Worm   375 FSASELNQMAPQAAACKTLWWQNLLYINNFDDGNSQNSTCYGITWYLAVDTQLYLVAPIVLVALY 439

  Fly   440 KWGKKAAAGIFVLIVLLSGCLFAT-IMVNKYSL---VLKNFSMDAQKDLYFATHTHATPW----- 495
               ...|||..:::....|.:..| |:...|::   ::.|  .|..|   |....::.||
Worm   440 ---FSFAAGTAIIVAGCVGSIITTYILFGVYNVPADIIGN--GDQTK---FFNIAYSKPWIRCPP 496

  Fly   496 -LTGFLFGYSLHLNRGKKFQLSKVVAWSGWILCLAMIFTSIFALYPYAKWTGPDLSTFAEASYYT 559
             |.|.|.||.|.....:|.:|:..:|.:|||....:....:||.|.|.|  |...|||..|::|.
Worm   497 YLVGLLTGYLLATYGSRKIRLNWALAIAGWITAFVIAGFCLFATYDYDK--GAHWSTFTRATFYN 559

  Fly   560 LTRVGWCMALCWVIFACMNGYGGLANSFLSSPLWQPLSRLSYSVYM--WHMFFQEINIRSMRTNS 622
            ..|:||.:.:|||:.|...|:||..:.|:|.|:|||..||||..|:  |.:.:..:|:..:...|
Worm   560 FHRLGWGVFVCWVVGANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWMVLYYYLNVGGVLHYS 624

  Fly   623 YFSNYTIMLNFWSTFGF----AVLFAYVM----HLVIEAPFGGLDYFL---------RPKQKTPP 670
                     :.|..|.:    |.|.:||:    ..:.|.|...|:..|         |...|...
Worm   625 ---------SAWQVFTYIAIPATLLSYVLAFFWSCLFEVPILKLEKMLIEKLIGGGGRTSLKVED 680

  Fly   671 LVKQKSQIDDNGHNN----LEELKV 691
            |.|...::.|....|    .|.|::
Worm   681 LGKNIGKVPDEEAENEKVQCEALRI 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10182	NP_651158.1	NRF	85..186	CDD:214781	27/109 (25%)
		Acyl_transf_3	269..645	CDD:280013	124/412 (30%)
		OafA	300..655	CDD:224748	115/392 (29%)
oac-32	NP_001300114.1	NRF	77..185	CDD:214781	29/119 (24%)
oac-32	NP_001300114.1	OafA	254..659	CDD:224748	130/438 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.680