DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10182 and oac-55

DIOPT Version :9

Sequence 1:	NP_651158.1	Gene:	CG10182 / 42780	FlyBaseID:	FBgn0039091	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_001317839.1	Gene:	oac-55 / 178792	WormBaseID:	WBGene00021479	Length:	742	Species:	Caenorhabditis elegans

Alignment Length:	768	Identity:	181/768 - (23%)
Similarity:	310/768 - (40%)	Gaps:	174/768 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 ALDFVGQVKDFDVEELSTLETRVPSQEDML----------------CLSDLTALTTGL------- 81
            |::.:|::....:|.:..||....|  |::                |..:|:.|..|:
Worm    31 AMELLGELIAHPIEVMEQLEKYKTS--DLIAALGIHSNANYSISQECHEELSFLGYGVIDAARYA 93

  Fly    82 --------------QSGQYWALKMFDSWGSIPSGLLTGNMYDLGNFDECLNIN-HGVSLGRTIQG 131
                          |..:.:.:.|.|:.|.:.||::.|::...|.|.||.:|. ...||.||:||
Worm    94 RHHSTAAVPASMTDQERKDYLIPMMDAAGKLGSGIVRGHILSTGAFSECKSIQMFSSSLNRTVQG 158

  Fly   132 KY--------------CFLSVSLAQALGVQSSIIGHFKTATCLPASCS----ATYMNTFMGMVTK 178
            .|              .|.|......:||.          .|||.||.    ..|....:|
Worm   159 DYYSSRILFDMKMRPNSFNSSCNLPQIGVD----------LCLPWSCRNEDLTGYFREALG---- 209

  Fly   179 QLLNVSIPSSVMSISESSCQTSESVP------WDGLTIFMIV----ILSVMGSLVALFTLWDYCL 233
                   ||..:|...|....::.||      |..|.|..::    |||....:...|.|.|
Worm   210 -------PSKALSPVCSVRNVNQRVPVISLGTWIVLLILSLIVGLCILSGFSDIFQKFQLND--- 264

  Fly   234 GKNQDQLPTIVKVFSA---RVNSRALFRIVEVNSSPNVIDCLHGIRCLSLMWVVF--CHQYVMAA 293
             |.:.:.....|:|||   ..|.:.:|.....:....|.. |:.||.:|..||:|  |.:.....
Worm   265 -KTRKEEGFGWKLFSAFSFHRNLKEIFNTKNCHKEGQVTS-LNCIRVISTFWVIFGHCSEITFMV 327

  Fly   294 LASNINIFHAISWEETPYASFILHGFFSVDSFFVLGGLLVALIPLRMMDRTKGKLNVP----LMY 354
            :.:.|:::...  ::|...:.|.:.:||||:||.:...|::.:..:.:::....|..|    :.|
Worm   328 ITNPIDLYDFT--KDTYTGTLISNAYFSVDTFFFISAFLLSFLWFKQLEKQWNALLSPGGWLMFY 390

  Fly   355 LHRLIRIVPLLAIAIVMYLKLMP-IVADGPRFGSGYSGTVD--CENGWYWTLLFVNNYTEEK--C 414
            :||:.|:.|:..:.|:.:..:.. .:.|.|.|.:  ...||  |:|.::..||::.|....|  |
Worm   391 VHRIARLSPVYYVTILFFTFVFTRSMVDMPAFMT--PAVVDDTCQNSYWVNLLYIQNIVGPKDIC 453

  Fly   415 LGHTWYLSVDMQLFILSPIMLIALYKWGKKAAAGIFVLIVLLSGCLFATIMVNKYSLVLKNFS-- 477
            ...:|||:.|:|::|:||::|::.      ...|..|.:::.:....|:...|.|.::..:|.
Worm   454 YFISWYLATDLQIYIMSPLILLSF------GLGGAVVGLLISTAAFLASTAFNAYQMIFWHFPPS 512

  Fly   478 ----------MDAQKDLYFATHTHATP------WLTGFLFGYSLHLNRGKKFQLSKVVAWSGWIL 526
                      .|..|..|.|.:.| .|      ::.|.:.||  .:.|..|..::..|....|.|
Worm   513 DYNYGPKDPLYDPSKRRYAAWNYH-NPLIRCQIYIMGMVLGY--FMRRIPKININPWVDRIMWCL 574

  Fly   527 CLAMIFTSIFALYPYAKWTGPDLSTFAEASYYTLTRVGWCMALCWVIFACMNGY-GGLANSFLSS 590
            .|..:...|..:..|.  :|...|....|.|...:||.|.:||.|::.:..  | .||.|.|:|.
Worm   575 SLGSMIFVIVIMEDYT--SGHLWSPLQTALYSCFSRVVWGLALSWIVISTY--YRKGLINKFMSL 635

  Fly   591 PLWQPLSRLSYSVYMWHMFFQEINIRSMRTNSYFSN--YTIML-------------NFWSTFGFA 640
            |:|.||:|||:..|:.|:...........:..|||.  |.:::             .||||. |.
Worm   636 PVWTPLARLSFCAYLVHLMVAAYFFGRNHSELYFSTLPYFVLVIAIPVISCSFLVAIFWSTM-FE 699

  Fly   641 VLFAYVMHLVIEAPFGGLDYFLRPKQKTPPLVKQKSQID---DNGHNNLEELK 690
            :.||.|..|::    ||     ..:...|.:  .|:.||   :|...|:|.::
Worm   700 LPFAKVEALLL----GG-----GSRSSAPDI--PKTPIDFPENNFEKNVESIR 741

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10182	NP_651158.1	NRF	85..186	CDD:214781	29/119 (24%)
		Acyl_transf_3	269..645	CDD:280013	105/420 (25%)
		OafA	300..655	CDD:224748	99/397 (25%)
oac-55	NP_001317839.1	NRF	111..220	CDD:214781	32/129 (25%)
oac-55	NP_001317839.1	OafA	299..690	CDD:224748	100/408 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.680