DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10182 and oac-39

DIOPT Version :9

Sequence 1:	NP_651158.1	Gene:	CG10182 / 42780	FlyBaseID:	FBgn0039091	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_001300160.1	Gene:	oac-39 / 178553	WormBaseID:	WBGene00006419	Length:	739	Species:	Caenorhabditis elegans

Alignment Length:	781	Identity:	172/781 - (22%)
Similarity:	311/781 - (39%)	Gaps:	180/781 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVNIVGVVFLCGLGLISAGRL----------------NDEDVLSDLQRVSQLKGLALDFVGQVKD 49
            ||.::.:..:..||::.:..|                :..:|:..|::......:|...:.....
Worm     1 MVELLVLFVVISLGIVPSNGLEFDPNKAMALLGELMAHPREVMEQLEKYKTSDLIAALGIHSFSK 65

  Fly    50 FDV-----EELSTL--------------ETRVPSQEDMLCLSDLTALTTGLQSGQYWALKMFDSW 95
            :.:     |||:.|              .|..||            ..|.::..:| .:.|.|:.
Worm    66 YTISEECHEELAFLGYGMIDVARHVKHQTTAAPS------------TMTDVEKTRY-LIPMMDAA 117

  Fly    96 GSIPSGLLTGNMYDLGNFDECLNIN-HGVSLGRTIQGKYCFL-------------SVSLAQALGV 146
            |.|.||:..|::...|.|.||.::: |..||.|||:|.|..:             |..|.| :||
Worm   118 GKIGSGIARGHILSAGAFTECKSVSMHSTSLNRTIRGDYYRILFDIKMRPNSFNDSCQLPQ-IGV 181

  Fly   147 QSSIIGHFKTATCLPASCS----ATYMNTFMGMVTKQLLNVSIPSSVMSISESSCQTSESVPWDG 207
            .          .|||.||.    ..|....:| .||:|      |.|.|:...:.:|      .|
Worm   182 D----------ICLPWSCRNEDLTDYFREALG-ATKEL------SPVCSVRNVNGRT------PG 223

  Fly   208 LT----IFMIVILSVMGSLVALFTLWDYCLGKNQDQLP------------TIVKVFSARVNSRAL 256
            .|    :.:.:|||::.:.:...|: ||.....:.::.            .|...||...|.:.:
Worm   224 FTFGTYVVVTLILSIIATSIVSCTV-DYYFQNRRSKIDYERMEGSSNVGWKIFMAFSLYRNVKEI 287

  Fly   257 FRIVEVNSSPNVIDCLHGIRCLSLMWVVFCHQYVMAALASNINIFHAISWEETPYASFILHGFFS 321
            |::.:.|....|.. |:.||.:|.:||:..|...|..|... |....:.:.:|...:.:::.:|:
Worm   288 FKMKQCNKEGQVTS-LNCIRTISTVWVILGHCAAMLILICT-NPVDLLDFTKTYMGALLVNAYFA 350

  Fly   322 VDSFFVLGGLLVALIPLRMMDRTKGKLNVP----LMYLHRLIRIVPLLAIAIV----MYLKLMPI 378
            ||:||.:...|::.:..:.:.:.:..|..|    :.|:||:.|:.|...|||:    :|::::
Worm   351 VDTFFFISAFLLSFLWFKQLQKQRKALISPGGWMMFYVHRIARLSPAYYIAILFVTFVYIRML-- 413

  Fly   379 VADGPRFGSGYSGTVDCENGWYWTLLFVNNYTEEK--CLGHTWYLSVDMQLFILSPIMLIALYKW 441
             .|.|.|.|.......|:..::..||::.|..:.|  |...:|||:.|:||:::|||:|::....
Worm   414 -RDMPAFMSPAIQDDTCQQNYWLNLLYIENIVDTKNICYVISWYLATDLQLYLMSPILLLSFAIG 477

  Fly   442 GKKAAAGIFVLIVLLSGCLFATIMVNKYSLVLKNF---------------SMDAQKDL--YFATH 489
            |  |..|:|..:|    .|.|:...|.|.:....|               ..:.:.|:  |:...
Worm   478 G--AVFGLFASVV----ALVASTAFNAYQIFFWYFPPTDYPLGPKDPRYNENERRYDVWNYYNPL 536

  Fly   490 THATPWLTGFLFGYSLHLNRGKKFQLSKVVAWSGWILCLAMIFTSIFALYPYAKWTGPDLSTFAE 554
            .....::.|.:.||  .:.:..|..::..|....|:|.|..:...:..:..|:  :|...:....
Worm   537 IRCQIYIMGLVLGY--FMRKVPKININPWVDRIMWVLSLGSMVFVVLVIQDYS--SGDGWTPVQT 597

  Fly   555 ASYYTLTRVGWCMALCWVIFACMNGY-GGLANSFLSSPLWQPLSRLSYSVYMWHMFFQEINIRSM 618
            |.|...:||.|..|:.|::.:..  | .||...|:|...|.||:|||:..|:.|...........
Worm   598 ALYSCFSRVLWGFAMSWIVISTY--YRKGLIRDFMSLSFWTPLARLSFCAYLVHWMVLGYFFGRN 660

  Fly   619 RTNSYFSNYT---------------IMLNFWSTFGFAVLFAYVMHLVIEAPFGGLDYFLRPKQKT 668
            .:..|||..:               ::..|||:             :.|.||..::..|..:..|
Worm   661 HSELYFSTLSYFFLDTVIPVTALSFVIAIFWSS-------------MFEIPFAKIEGLLLGRSGT 712

  Fly   669 P 669
            |
Worm   713 P 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10182	NP_651158.1	NRF	85..186	CDD:214781	35/118 (30%)
		Acyl_transf_3	269..645	CDD:280013	96/418 (23%)
		OafA	300..655	CDD:224748	87/397 (22%)
oac-39	NP_001300160.1	NRF	109..218	CDD:214781	38/127 (30%)
oac-39	NP_001300160.1	OafA	297..685	CDD:224748	94/404 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.680