DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10182 and oac-46

DIOPT Version :9

Sequence 1:	NP_651158.1	Gene:	CG10182 / 42780	FlyBaseID:	FBgn0039091	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_495886.2	Gene:	oac-46 / 174415	WormBaseID:	WBGene00011768	Length:	676	Species:	Caenorhabditis elegans

Alignment Length:	749	Identity:	167/749 - (22%)
Similarity:	293/749 - (39%)	Gaps:	156/749 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IVGVVFLCGLGLISAGRLNDEDVLSDLQRVSQLKGLALDF-----VGQVKDF--DVEELSTLETR 61
            |:|:..|.....|::..|.:.|....||.:::.:.|.|..     :..|.|:  |:|.|:
Worm     2 ILGLYLLLLSPAIASAGLEEYDEPFILQFINRSQTLDLSLKCKQSLALVYDYLNDIETLT----- 61

  Fly    62 VPSQEDMLCLSDLTALTTGLQSGQYWALKMFDSWGSIPSGLLTGNMYDLGNFD--ECLNINHGVS 124
                :..:|                    .|:|:.:.|:.|......|...:.  |||     :|
Worm    62 ----DQKIC--------------------YFESFATGPNDLFLSRDQDRWVYKGYECL-----LS 97

  Fly   125 LGRTIQGK------YCFL----SVSLAQALGVQSSIIGHFKTATCLPASCSATYMNTFMGMVTKQ 179
            .|.|:..|      ||:.    ......|..|            |:|:.|:.....     :.::
Worm    98 AGETVYSKSEHPMHYCYTHDDDKDKRVPAFSV------------CIPSPCADENQK-----LLEE 145

  Fly   180 LLNVSIPSSVMSISESSCQTS-ESVPWDGLTI------FMIVILSVMGSLVALFTLWDYCLGKN- 236
            ...::.|.:...|:.::|..| ....|..|.:      |.:    .:..||.:.|::....|::
Worm   146 WRRITHPEATEPITFTACTRSRHEKQWFELPVPIADFGFNM----SLAMLVVMATIFHNMRGEDA 206

  Fly   237 QDQLPTIVKVFSARVNSRALFRIVEVNSSP-NVIDCLHGIRCLSLMWVVFCHQYV-MAALASNIN 299
            :.....|:..|||:.|   |.:::.:...| :.|.||.|:|..|::|.:..|.:: :.|...|:.
Worm   207 KSWSARILLAFSAKTN---LKKLIALPKDPQSCITCLLGLRFGSMVWTLIGHSFIFVQAYMENVE 268

  Fly   300 IFHAISWEETPYASFILHGFFSVDSFFVLGGLLVALIPLRMMDRTKGKLNVPL---------MYL 355
            .|.. |..:..:..:|.:...|||.|..|||.:::....|...:...: ..|.         .|.
Worm   269 DFKN-SMVDNFFNQWITNFTLSVDVFLTLGGTVLSYSWFRKWLKNTSE-EEPTWTSWGYWLKFYR 331

  Fly   356 HRLIRIVP-----LLA----IAIVMYLKLMPIVADGPRFGSGYSGTVDCENGWYWTLLFVNNYTE 411
            ||::|:.|     |||    |::..:..:.|..          ...:.|...|:..:||||:..:
Worm   332 HRVVRLYPAYLYTLLAVTLRISVTHFHPMWPPT----------DPAIQCPKYWWQNVLFVNSILD 386

  Fly   412 EKCLGHTWYLSVDMQLFILSPIMLIALYKWGKKAAAGIFVLIVLLSGCLFATIMVNKYSLVLKNF 476
            .:|:..|||:..:...::||||.|:.|.|..|......||:|:..:|       :|..|:|..||
Worm   387 NQCMPWTWYIGTEFIYYLLSPIFLLTLRKAPKIGFILCFVVIMFSAG-------LNVESIVRNNF 444

  Fly   477 S----------------MDAQKDLYFATHTHATPWLTGFLFGYSL--HLNRGKKFQLSKVVAWSG 523
            .                :....:||........|:|.|.|.||.|  :.....|.|.|.....|.
Worm   445 PPTQFLWKQPEMFNPNFIQHHLELYIKPQYRIGPYLIGILLGYQLARYQRIPVKPQQSNKYIISM 509

  Fly   524 WILCLAMIFTSIFALYPYAK-WTGPDLSTFAEASYY----TLTRVGWCMALCWVIFACMNGYGGL 583
            |.:.|..|...::.|||..: |     .:.|..:|:    .|.|..:.:.:.::|:.|..|.||.
Worm   510 WSVALVGILFGLYGLYPALQGW-----DSIAWRAYHLLYGALHRDIFSIGIAFLIYICHTGIGGP 569

  Fly   584 ANSFLSSPLWQPLSRLSYSVYMWHMFFQEINIRSMRTNSYF-SNYTIMLNFWSTFGFAVLFAYVM 647
            .|.||||..:.||:.||:|.|::||....:....:....|| :...:.::.:........||.:.
Worm   570 VNVFLSSNFFLPLANLSFSAYLFHMIPVVLTYMLVPFPIYFNTQIPLFIHCFVQLLITYFFAIIC 634

  Fly   648 HLVIEAPFGGLDYFL---RPKQKTPPLVKQKSQI 678
            .:|.|.|...::..|   .||....|.....|:|
Worm   635 TMVSELPALNIERLLLASPPKTTLKPSPPTDSEI 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10182	NP_651158.1	NRF	85..186	CDD:214781	19/112 (17%)
		Acyl_transf_3	269..645	CDD:280013	104/418 (25%)
		OafA	300..655	CDD:224748	97/396 (24%)
oac-46	NP_495886.2	OafA	279..653	CDD:224748	97/396 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.780