Protein Alignment CG10182 and nrf-6

DIOPT Version :10

• Sequence 1: NP_651158.1
• Gene: CG10182 / 42780
• FlyBaseID: FBgn0039091
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_495680.1
• Gene: nrf-6 / 174287
• WormBaseID: WBGene00003813
• Length: 822
• Species: Caenorhabditis elegans
• Alignment Length: 775
• Identity: 188/775 - (24%)
• Similarity: 323/775 - (41%)
• Gaps: 172/775 - (22%)

  Fly    35 QLKGLALDFVGQVKDFDVEELSTLETRVPSQEDMLCLSDLTALT-TGLQ---------------- 82
            :|...|::.|.::|.||:              .|.|:.|:..|. ||::
 Worm    90 ELMKYAVEMVEKLKSFDI--------------SMACVGDMMHLAWTGVEYATHVEEHKNCSDCKC 140

  Fly    83 --------SGQYWALKMFDSWGSIPSGLLTGNMYDLGNFDECLNINHGVSL-GRTIQGKYCFLSV 138
                    |.::|...:||:.|.:|:|:::||...:|::..|..|:...:. |:..:|:||..::
 Worm   141 TPLFQQKKSERHWIFNVFDAMGKVPAGIMSGNNLWVGSWSTCRKIDVVKNAQGQKWKGQYCLATI 205

  Fly   139 SLAQA-----------------------------LGVQSSIIGHFKTATCLPASCS---ATYMNT 171
            ...:.                             .|...::....|...|:|.:|:   ...|.:
 Worm   206 DAYERDNPLVYFGNMMSGPPDKHCYDKTVKNVTDDGFCFALFPVLKFGVCMPNTCTNHDVKQMLS 270

  Fly   172 FM-----GMV-TKQLLNVSIPSSVMSISESSCQTSESVPWDGLTIFMIVILSVMGSLVALFTLWD 230
            |.     |.| ||.:.||.:.....|.|::..:       :||.:|.:.:|.....||...||:|
 Worm   271 FAIRATEGAVGTKSVCNVDVECRAESYSDAMSE-------NGLAMFALYLLIATVVLVTFGTLYD 328

  Fly   231 -YCLGK-NQDQL-------PTI--VKVFSARVNSRALFRIVEVNSSPNVIDCLHGIRCLSLMWVV 284
             :.:.| .||:.       |.|  :..||...|..   .|::...:...|:.|||:|.||:.|::
 Worm   329 LFIVSKAPQDEKNSSAFNHPFIKFILAFSMYTNGS---EILQSKKNDREINSLHGVRFLSMCWII 390

  Fly   285 FCH--QYVMAALASNINIFHAISWEETPYASFILHGFFSVDSFFVLGGLLVALI----PLRMMDR 343
            ..|  .|:..:|.::..:...|::.:..:...|:....:|||||.|.|:|.|..    .::....
 Worm   391 LGHTYYYIGTSLTTDNLVPTLINFPKQFHTQIIVQAPLAVDSFFFLSGMLAAFSFFKKTMKADPN 455

  Fly   344 TKGKLNV------PLMYLHRLIRIVPLLAIAIVMYLKLMPIVADGP------RFGSGYSGTVDCE 396
            ...||:.      |:.|..|.|||.|...|.::..:.|...:::||      |.|        |.
 Worm   456 HPPKLSAFNWQTWPMYYYKRYIRITPTYIIVMLFDVTLFTYISNGPFWRPIERQG--------CS 512

  Fly   397 NGWYWTLLFVNNY---TEEKCLGHTWYLSVDMQLFI-LSPIMLIALYKWGKKAAAGIFVLIVLLS 457
            ..|:..|:::||:   .:|.|:|.||||:.|||..| |.|:::|...|||.|...|:...::.||
 Worm   513 IAWWTNLIYLNNFLLQDQECCMGWTWYLANDMQFHIFLMPLLVIVFLKWGMKVGLGLSTGLIALS 577

  Fly   458 GCLF-----------ATIMVNKYSLVLKNFSMDAQKDLYFATHTHATPWLTGFLFGYSLHL---- 507
            ..:.           |.|:..|..:|.:  ..|...|:|...:...||::.|.:..|.|:.
 Worm   578 SLIRLIITQIYGYPPAPILTAKLQIVYQ--LNDYWNDVYVRPYIRCTPFIVGIVVAYLLNAWTTR 640

  Fly   508 -NRGKKFQLSK---VVAWSGWILCLAMI--FTSIFALYPYAKWTGPDLSTFAEASYYTLTRVGWC 566
             .:..|.:|.:   ::.|     |.:.:  ..|:|.||.:|| || |:|...|..|.......:.
 Worm   641 EQKDLKIKLERRTVIICW-----CTSTVLGLYSVFGLYWFAK-TG-DISKPWEILYTIFGTPAYA 698

  Fly   567 MALCWVIFACMNGYGGLANSFLSSPLWQPLSRLSYSVYMWHMFFQEINIRSMRTNSYFSNYTIML 631
            :||.||:|||..|.||..::.||..|:.|||::::..|:.|....:|...|.....:|:.:..|:
 Worm   699 LALGWVVFACTTGNGGPVDTILSWRLFVPLSKITFCAYLLHPIMLQIYNLSRPQPFHFTTFIQMI 763

  Fly   632 NFWSTFGFA-VLFAYVMHLVIEAPFGGLDYFLRPKQKTPPLVKQKSQIDDNGHN-NLEEL 689
            .:.....|| ...|:...|..|.|...:|..|...:|..           ||.| |..|:
 Worm   764 RYTVEAVFASYTIAFFFSLAFEKPLNKIDEMLFNSKKMM-----------NGENGNTTEM 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10182	NP_651158.1	NRF	70..173	CDD:466307	27/160 (17%)
		OafA	264..655	CDD:441440	118/434 (27%)
nrf-6	NP_495680.1	NRF	151..288	CDD:214781	26/136 (19%)
		OafA	370..790	CDD:441440	119/436 (27%)