Protein Alignment Ugt303B2 and UGT8

DIOPT Version :10

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_003351.3
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 148/550 - (26%)
• Similarity: 262/550 - (47%)
• Gaps: 87/550 - (15%)

  Fly     7 WLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTM-------VTPAD 64
            |.|.|          :.:||.|:.|.|....|...:.:.|..||.||||....       :.|::
Human    12 WSAVG----------IAKAAKIIIVPPIMFESHMYIFKTLASALHERGHHTVFLLSEGRDIAPSN 66

  Fly    65 ------YPAKIDGVRHIRVPMLNQLMQNLMKN--------DQFFDALGDKWREGVLVSTIFYNVS 115
                  ||...:....      :..:|:.|:|        .:.||.| |.:.:         |..
Human    67 HYSLQRYPGIFNSTTS------DAFLQSKMRNIFSGRLTAIELFDIL-DHYTK---------NCD 115

  Fly   116 HAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLA--GNL 178
            ..:.|:..:|.|.::|   ||:::|:.:      .:..|..|.|||:.....:..:.|.|  |..
Human   116 LMVGNHALIQGLKKEK---FDLLLVDPN------DMCGFVIAHLLGVKYAVFSTGLWYPAEVGAP 171

  Fly   179 APSVYEPISPNGFALDN-TFLSRWSNWIYITEEKLLERL----VFRPAQVRLFKKFFGYPAEKLD 238
            ||..|.| ..|....|. ..|.|..|    |...|:.||    :..|...|:.:|:...|.:.:.
Human   172 APLAYVP-EFNSLLTDRMNLLQRMKN----TGVYLISRLGVSFLVLPKYERIMQKYNLLPEKSMY 231

  Fly   239 ELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEA-EHGAIYFSMGQ 302
            :|....|:.::.:..::...|..:||::.|.|: |::|..|...:||::::.| |||.:..|.|.
Human   232 DLVHGSSLWMLCTDVALEFPRPTLPNVVYVGGI-LTKPASPLPEDLQRWVNGANEHGFVLVSFGA 295

  Fly   303 DILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITH 367
            .  :|||.|::..:|.....::.|:|||:.......|...|..:::.:||..:|.|..::.|::|
Human   296 G--VKYLSEDIANKLAGALGRLPQKVIWRFSGPKPKNLGNNTKLIEWLPQNDLLGHSKIKAFLSH 358

  Fly   368 GGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYA 432
            |||.|:.|.|.:|||::|:|||.|.::.:.|||..||..:|:...:....|.|.:.:::.||||.
Human   359 GGLNSIFETIYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINNPSYR 423

  Fly   433 QRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCV 497
            |||::::...:|:|..|::..|:|.:|.:|:....|:|..|.:|...:|:.||  :.|.:.||
Human   424 QRAQKLSEIHKDQPGHPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLLD--IAFVLLLG-- 484

  Fly   498 CGSLIF--LGW---RLYQK-----NRNRHT 517
             .:|::  |.|   .:|:|     :||:|:
Human   485 -AALLYFLLSWVTKFIYRKIKSLWSRNKHS 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	Glycosyltransferase_GTB-type	24..464	CDD:471961	127/468 (27%)
UGT8	NP_003351.3	Glycosyltransferase_GTB-type	21..502	CDD:471961	140/518 (27%)