Protein Alignment Ugt303B2 and UGT2B17

DIOPT Version :10

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001068.1
• Gene: UGT2B17 / 7367
• HGNCID: 12547
• Length: 530
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 136/533 - (25%)
• Similarity: 258/533 - (48%)
• Gaps: 64/533 - (12%)

  Fly     7 WLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPAD----YPA 67
            |::..||:.|:.|...|....:| |:|... |.:..::.:::.||:|||:|.::|.:.    ..:
Human     5 WMSVFLLMQLSCYFSSGSCGKVL-VWPTEY-SHWINMKTILEELVQRGHEVIVLTSSASILVNAS 67

  Fly    68 KIDGVRHIRVPMLNQLMQNLMKND--QFFDALGDKWREGVLVSTIF---------------YNV- 114
            |...::      |.....:|.|||  .||..:.|:|...:..:|.:               ||:
Human    68 KSSAIK------LEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYNIK 126

  Fly   115 --SHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMH-MTWHIDYL-- 174
              ..|:||...::.|...|   ||:::.     ||:....|.. |.||.|..:: :.:.:.|.
Human   127 LCEDAVLNKKLMRKLQESK---FDVLLA-----DAVNPCGELL-AELLNIPFLYSLRFSVGYTVE 182

  Fly   175 ---AGNLAPSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFF----GY 232
               .|.|.|..|.|:..:..:....|:.|..|.||:    |.....|:...::.:.:|:    |.
Human   183 KNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIYM----LYFDFWFQAYDLKKWDQFYSEVLGR 243

  Fly   233 PAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEA-EHGAI 296
            |. .|.|...:..:.|:.:::.....|..:||:..|.|:| .:|.:|...|:::::..: |:|.:
Human   244 PT-TLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLH-CKPAKPLPKEMEEFVQSSGENGIV 306

  Fly   297 YFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNL 361
            .||:|.  :|..:.|.....:.....|:.|:|:|:.:.........|..:...:||..:|.||..
Human   307 VFSLGS--MISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKT 369

  Fly   362 RLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELL 426
            :.||||||...:.|||.:|:||:|:|||.||.:||..::..|.|..:|...:::..|:..:|.::
Human   370 KAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVI 434

  Fly   427 ENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSILTFG 491
            .:|.|.:...:::....|:|:.|||.|::|.|:.:|::...|:|:....:..::|:.|| ::.|
Human   435 NDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLD-VIAF- 497

  Fly   492 VRLGCVCGSLIFL 504
             .|.|| .::||:
Human   498 -LLACV-ATMIFM 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	Glycosyltransferase_GTB-type	24..464	CDD:471961	119/474 (25%)
UGT2B17	NP_001068.1	UDPGT	24..518	CDD:278624	130/514 (25%)