Protein Alignment Ugt303B2 and UGT1A9

DIOPT Version :9

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_066307.1
• Gene: UGT1A9 / 54600
• HGNCID: 12541
• Length: 530
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 131/508 - (25%)
• Similarity: 249/508 - (49%)
• Gaps: 48/508 - (9%)

  Fly    43 VRPLIKALVERGHKVTMVTPADYPAKIDGVRH--IRVPMLNQLMQNLMKNDQFFDALGD-KWREG 104
            :|.:::.|:.|||:|.:|.| :...::....:  ::....:..:::|   |:.|.|... :|:..
Human    41 MRSVVEKLILRGHEVVVVMP-EVSWQLGRSLNCTVKTYSTSYTLEDL---DREFKAFAHAQWKAQ 101

  Fly   105 V--LVSTIF--YNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLL----- 160
            |  :.|.:.  ||....:..:| .:.|.:||.:   :..::.|..||:: |..|.|..|:
Human   102 VRSIYSLLMGSYNDIFDLFFSN-CRSLFKDKKL---VEYLKESSFDAVF-LDPFDNCGLIVAKYF 161

  Fly   161 ---------GISCMHMTWHIDYLAGNLAPSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERL 216
                     ||.| |   :::..|...||..|.|....||:...||..|..|.|...||.||...
Human   162 SLPSVVFARGILC-H---YLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHR 222

  Fly   217 VFRPAQVRLFKKFFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCG 281
            .|:.| :.:..:....|..:.| |.:..|:.|:.:.|.:...:..:||:|.:.|::..: .:|..
Human   223 FFKNA-LEIASEILQTPVTEYD-LYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQ-GKPLP 284

  Fly   282 AELQKYLD-EAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIY 345
            .|.:.|:: ..|||.:.||:|.  ::..:||.....:.....::.|.|:|:...:..:|.:.|..
Human   285 MEFEAYINASGEHGIVVFSLGS--MVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTI 347

  Fly   346 VMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDP 410
            ::..:||..:|.||..|.||||.|...|.|:|.|||||:.:|||.||.:|..|::..|....|:.
Human   348 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNV 412

  Fly   411 NDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEE 475
            .::.::.|...:|.::.:.||.:....:::..:|||:.|||.|::|.|:.:|::...|:|....:
Human   413 LEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHD 477

  Fly   476 IPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRL----YQKNRNRHTRLQERER 524
            :...:|:.||.|   |..|..|. ::.|:.::.    |:|...:..|:::..:
Human   478 LTWYQYHSLDVI---GFLLAVVL-TVAFITFKCCAYGYRKCLGKKGRVKKAHK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	118/442 (27%)
UGT1A9	NP_066307.1	UDPGT	26..521	CDD:278624	130/501 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150358
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.690