DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and Ugt37C1

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	134/500 - (26%)
Similarity:	227/500 - (45%)	Gaps:	87/500 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KALVERGHKVTMVTPADYPAKIDGVRHIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFY 112
            |||.|.||.||:|:..........:..|.||:..:..:.|  .:|.....|.|   ..:::|::
  Fly     5 KALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTL--ENQMASMAGSK---NNIITTMY- 63

  Fly   113 NVSHAILNNNGVQM-----LMRDK------SIRFDMIMVEASHLDALYGLAEFYNATLLGISCMH 166
                .:||...|.:     |::|.      ..:||:::           |..|:|...||:
  Fly    64 ----LLLNGLDVMVTSQADLLKDPRFQRVFETKFDLMI-----------LGSFFNDFQLGV---- 109

  Fly   167 MTWHIDYLAGNL-APSVYEPISPNGFALDNTFLSRWSNWIYITE---------------EKLLER 215
                    ||.| .|.:.:.:.|:...:|. |::..|...|:..               |.|::.
  Fly   110 --------AGKLKVPVIVDWMIPSNTMIDE-FVANPSEVSYVPNESTFATTPMSFFKRAENLVKH 165

  Fly   216 LVFRPAQVRLFKKFFGYPAE--------KLDELRARFSVILVNSH-FSMGRVRANVPNIIEVAGV 271
            ::.:...:|...||.....|        .|.|::...|::.|.|| .|.|.:|..||.||||.|:
  Fly   166 VILKYLTIRFNYKFNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGI 230

  Fly   272 HLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWK-SELS 335
            .:.|.|:|...:::::::.:..|||:.|.|.:|....:...:...:..|...:||.|||| .:|.
  Fly   231 QVKEQPDPLPQDIEQFMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLE 295

  Fly   336 MLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQ 400
            .....:.||:..|.:||..:|||||.:||:||.|..|:.|:..:||||:.||:|.|...|...:.
  Fly   296 NTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMV 360

  Fly   401 LAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRD 465
            .:|....||...:..||..|.|.|:|||..|.|..::.:|.:||||::|..:.::|.:|.||:..
  Fly   361 NSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHG 425

  Fly   466 TSHMRLNVEEIPLMRYYRLD------SILTFGVRLGCVCGSLIFL 504
            ..:::.....:..:..:.||      :||.|          |:||
  Fly   426 APNLQSPAVHMGFVELHNLDIYALVLAILIF----------LVFL 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	126/452 (28%)
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	133/499 (27%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	125/460 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445741
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.850