DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and Ugt37E1

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_652628.2	Gene:	Ugt37E1 / 53512	FlyBaseID:	FBgn0040261	Length:	539	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	151/532 - (28%)
Similarity:	254/532 - (47%)	Gaps:	76/532 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYP--A 67
            |..:.|.:...|:...:....|||||||....||...:...::|||.:|||.:|:||... |  |
  Fly     4 YTKIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMK-PKLA 67

  Fly    68 KIDGVRHIRVPMLNQLMQNLMKNDQFFDALGDK---WR---EGVLVSTIFYNVSHAILNNNGVQM 126
            ..:.:..|..|...: .|..:| :...:...:|   |.   :.::.|:......:..:.:..|:.
  Fly    68 THENITVIIAPPTEE-RQRYIK-EYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTHPNVKE 130

  Fly   127 LMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISC-----MHMTW------HIDYLAGNLAP 180
            :..:..|:||::.:         ||  ..|...|||:.     :.::|      .:|.:.||:..
  Fly   131 IYENPKIKFDLVFL---------GL--MANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVND 184

  Fly   181 SVYEP---ISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYP--------- 233
            ..|.|   ::.|.......|..|:.|:             |:.|.:.:|:....|.
  Fly   185 PSYVPTVNVALNAGQKTMDFGLRFVNF-------------FKYAIMCVFETVLDYKMNQFYERAF 236

  Fly   234 AEKLD-----ELRARFSVILVNSH-FSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAE 292
            |.:|:     |::.|.|::..|.| .|.|.:|..||..||:.|:.:.|..:|...||.|:||:|:
  Fly   237 ANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKAD 301

  Fly   293 HGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANK---SENIYVMDKVPQRM 354
            .|||:||:|.::.......:....|..|..::.||||||.|  .|.||   :.||:..:.:||..
  Fly   302 EGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWE--DLKNKPGNASNIFFGNWLPQDD 364

  Fly   355 VLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLI 419
            :|||||.:|||||.|...|.||..:||||:.||:|.||..|...:..:|..:.||...:....|.
  Fly   365 ILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELE 429

  Fly   420 ETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLM--RYY 482
            :||:|:|.||:|.:...:.:..:||||::...:.|:||||.||::...|:     :.||:  ::.
  Fly   430 QTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHL-----QSPLIHTKFV 489

  Fly   483 RLDSILTFGVRL 494
            ..:::..:||.|
  Fly   490 ARNNLDVYGVVL 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	142/479 (30%)
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	144/496 (29%)
Ugt37E1	NP_652628.2	YjiC	27..448	CDD:224732	129/449 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445755
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.850