DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and Ugt302C1

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster

Alignment Length:	517	Identity:	156/517 - (30%)
Similarity:	273/517 - (52%)	Gaps:	28/517 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKID 70
            |.|.|.||..::.|       |.|.|......|.:.:...|.|.|...||:||:::|.:....|.
  Fly    12 ALLLFCLLSCVSAY-------NYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIK 69

  Fly    71 GVRHIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYN-----VSHAILNNNGVQMLMRD 130
            .::.:....:...||..:.|      |....:|.::...|.::     ::..:|....|..||:.
  Fly    70 NIKDVPAKSILTSMQGRIAN------LLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKS 128

  Fly   131 KSIRFDMIMVEASHLDALYGLAEFYNATLLGISCM-HMTWHIDYLAGNLAPSVYEPISPNGFALD 194
            .. .||.::.|....:|.:|.||.:.|.|:|:... .::|:.| |.|:.:|..|.|.:...|:..
  Fly   129 NQ-TFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTD-LVGSPSPPSYVPSALLKFSDR 191

  Fly   195 NTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEKLD--ELRARFSVILVNSHFSMGR 257
            .:.:.|..|..::|.|.:.....:.|.|..|::|:|  |..|.|  ::|...:::|:|.|.|:..
  Fly   192 MSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYF--PNNKQDFYDMRKNTALVLLNQHVSLSF 254

  Fly   258 VRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFL 322
            .|...||:|||.|:|::...:|...::.::::.||||.||||||.::..|.||...::.|:..|.
  Fly   255 PRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALIDTFA 319

  Fly   323 QMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLP 387
            |:||||:||.|.:.|..|..|:::.|..||..:|||.|:..|||||||.|..|:|.:..|.:|:|
  Fly   320 QLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIP 384

  Fly   388 LFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDT 452
            :|.|||.|:.|.:..|....:...:|::..|:..|::::.||...||.::|:..:||:..:||:.
  Fly   385 IFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLER 449

  Fly   453 AIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSILTF--GVRLGCVC-GSLIFLGWRLYQK 511
            |::|.|:..|::...::|...:::..::|:.||::|..  |:.....| ..||.|.|||.|:
  Fly   450 AVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQE 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	136/447 (30%)
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	117/352 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445613
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.800