DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and Ugt35C1

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001097744.1	Gene:	Ugt35C1 / 53507	FlyBaseID:	FBgn0040256	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	158/472 - (33%)
Similarity:	257/472 - (54%)	Gaps:	22/472 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKIDGVRHIRVPMLNQLMQNLM 88
            ::|.||...|:...|.:..|...:|||..:||:||:         |:..::...|  |......:
  Fly    22 ESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTV---------INAFKNKETP--NMRFIEAL 75

  Fly    89 KNDQFFDALGD------KWREGVLVSTIFYNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDA 147
            |..:|.|.:..      .|::...:..|........:.:.|||.|: :....||:::.|..|::.
  Fly    76 KAHEFADEMMSLLNVPLLWQQLNAMDYILNKFIDVTMEDEGVQRLL-NSGETFDLVLAEMLHMEP 139

  Fly   148 LYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPI--SPNGFALDNTFLSRWSNWIYITEE 210
            :|..|:.:||||:|.|.......||..|||::|..|.|:  ||....:  |||.|..|...:..|
  Fly   140 MYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPLVTSPRTDRM--TFLERLENHYEVIVE 202

  Fly   211 KLLERLVFRPAQVRLFKKFFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSE 275
            .:....|..|....::||:|....:.|:|:...||:||:..|||:...|..:||:|||.|:|:|.
  Fly   203 DIHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISH 267

  Fly   276 PPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANK 340
            .|:|...:::::::.:.||.||||||.::..|.||:..:..||..|.::||||:||.|...:..|
  Fly   268 KPKPLPEDIKQFIEGSPHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGK 332

  Fly   341 SENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMA 405
            ..|:.:....||..:|||||::|||:||||.|..|::..|.|:||||.|:||..|:.|.|..|..
  Fly   333 PANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFG 397

  Fly   406 KVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMR 470
            ..||.|:|..:.|.:.|:.||.:||||:.:..::..:||:|.|.:|.|:|||||.:|:....|:|
  Fly   398 LGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLR 462

  Fly   471 LNVEEIPLMRYYRLDSI 487
            ....::..::...||::
  Fly   463 ATSRDLNFIQLNSLDTL 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	154/447 (34%)
Ugt35C1	NP_001097744.1	egt	1..470	CDD:223071	156/461 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	10	9.870