DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and Ugt35E1

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	182/546 - (33%)
Similarity:	296/546 - (54%)	Gaps:	49/546 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LAFGLL-LHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKIDG 71
            ||.||. |.:.|:......|.||.:||....|.:....|.:|.|...||::|.|:|......:..
  Fly     2 LASGLFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKN 66

  Fly    72 VRHIRVP-MLN---QLMQNLM--KND-QFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQM-LM 128
            :..|.|| :||   :|::.:.  ||. :||||..:          ..||::..:.||:||:. ::
  Fly    67 IYDIYVPEVLNSFDELLKQMTTPKNTWEFFDATNE----------FVYNITKDVFNNDGVRREIL 121

  Fly   129 RDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPISPNGFAL 193
            |....:||:|:|:....||.|.||.::.|.::|::...:.|.||.:.||.:|..|.. ||:.:..
  Fly   122 RPGKAQFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQ-SPSSYLY 185

  Fly   194 D-NTFLSR----------WSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAE--KLDELRARFS 245
            : :||..|          |.||.:..|:|          ...|:||:|...||  .|.|:....:
  Fly   186 NLDTFGGRVAHVVEVAISWFNWHWRYEQK----------HEALYKKYFPKIAETKPLSEISQDIA 240

  Fly   246 VILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLD-EAEHGAIYFSMGQDILIKYL 309
            ::|||.||::|..|..|||:|||.|:|:.|.|:....:|:.::. ..|||.||||:|.::..|.:
  Fly   241 LVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNM 305

  Fly   310 PENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVM 374
            .::.::.|:..|..:.|||:||.|...|.:...|:.|...:||:.:||||.::|||||||:||.:
  Fly   306 VDDRKRILIEAFGSLPQRVLWKFEDEELQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTI 370

  Fly   375 EAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMA 439
            |:|..|.||||||.|:|||.|:..::..|....|:.:|:.:|.|..||.:||....:...|:...
  Fly   371 ESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAG 435

  Fly   440 ASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSILT-FGVRLGCVCGSLIF 503
            |.:||:||.||:||:|||.|.||::...|||:...::....::.||.:.| ..|.|..:...|:.
  Fly   436 ARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLI 500

  Fly   504 LGWRLYQKNRNRHTRL----QERERV 525
            :.:.:.:.::|..|||    |.:::|
  Fly   501 IVFSVCKISKNISTRLVVKKQRKQKV 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	161/461 (35%)
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	164/475 (35%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	161/471 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445589
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.800