DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and Ugt37A3

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650229.2	Gene:	Ugt37A3 / 41574	FlyBaseID:	FBgn0038083	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	150/514 - (29%)
Similarity:	245/514 - (47%)	Gaps:	17/514 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLHLNLYLELG--QAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKIDGVRH 74
            |||.:.:...:|  |.|||||:||...||...:.....|.|.|.||.||:||..........:..
  Fly     9 LLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITV 73

  Fly    75 IRVPMLNQLMQN-------LMKNDQFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQMLMRDKS 132
            |:||:..:..|.       :.|||....||........:...|..|..  .|.|:.|:.|..::.
  Fly    74 IQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAE--TLMNDRVRDLYLNRG 136

  Fly   133 IRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPIS-PNGFALDNT 196
            .:||:::......|...|.|...||.::.::.|.....::.|.||.....|..|| |...:...|
  Fly   137 NKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGISNPAEGSKAVT 201

  Fly   197 FLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAE--KLDELRARFSVILVNSH-FSMGRV 258
            |..|.|:::......:...|..|..: ..:|:.:|...:  :..|:....|::..:|| .|.|.:
  Fly   202 FQRRLSSYMQSLGFGVFSHLSERRNR-NWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPI 265

  Fly   259 RANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQ 323
            |.|||:.||:.|:.:.:.|:|....:.::|..|..|||..|:|.::..|:|..:...::..|..:
  Fly   266 RPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATDGAILLSLGSNVQGKHLNPDTVAKMFNVLSK 330

  Fly   324 MKQRVIWK-SELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLP 387
            :|:||||| .:......||.||.....:||..:|||||::|||.|.|...:.|:..:|.|||.||
  Fly   331 LKERVIWKWEDQENTPGKSANILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLP 395

  Fly   388 LFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDT 452
            :|.||..|.:.:..:|....|....|......|.|.|:|.||.||:|.|..:..:|||||:..::
  Fly   396 VFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARES 460

  Fly   453 AIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRLYQK 511
            .::||||.:|:...:|::..:..:..:....:|......|.|..|...:.||...:|::
  Fly   461 FLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVILVSVLVLIKFLVQFIYRR 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	138/451 (31%)
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	143/483 (30%)
Ugt37A3	NP_650229.2	UDPGT	37..526	CDD:278624	137/486 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445783
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2882
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	9.000