DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and Ugt37A2

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650228.1	Gene:	Ugt37A2 / 41573	FlyBaseID:	FBgn0038082	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	135/490 - (27%)
Similarity:	228/490 - (46%)	Gaps:	55/490 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LYLELGQA---------ANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKIDGVR 73
            :||.|..|         |||||||....||...:.....|.|.||||.||::|..........:.
  Fly     7 IYLLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNIT 71

  Fly    74 HIRVPMLNQLMQNLMKNDQFFDALGDKWR---EGVLVSTI--------FYNVSHAILNNNGVQML 127
            .|.||:..:      ::.|..|.:|...:   ..:::|.:        .::.....|.::.|:.|
  Fly    72 VIMVPLTKE------ESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALKDDRVRDL 130

  Fly   128 MRDKSIRFDMIMVEASHLDALY--GLAEFYNATLLGISCMHMTWHIDYLAGN-----LAPSVYEP 185
            ..::..:||:::  :.:...:|  |.|:...|.::.::.|.....::.|.||     ..||:.:.
  Fly   131 YLNRDNKFDLVL--SGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDS 193

  Fly   186 ISP-NGFALDNTFLSRWSNWI-----YITEEKLLERLVFRPAQVRLFKKFFGYPAE--KLDELRA 242
            :.. .|.:.........|::.     ::|:.:          ..||:|:.||....  :..||..
  Fly   194 VEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRR----------SKRLYKELFGDDPNMPEYSELVK 248

  Fly   243 RFSVILVNSHF-SMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILI 306
            ..|:|...||. |.|.:|.|||..||:.|:.:.:.|:|....:.::|..|..|||..|:|.::..
  Fly   249 NTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATDGAILLSLGSNVKG 313

  Fly   307 KYLPENMQKQLLLVFLQMKQRVIWK-SELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGL 370
            .::..:...::..|..::||||||| .:|.....||:||:....:||..:|||||::|||.|.|.
  Fly   314 SHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGK 378

  Fly   371 QSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRA 435
            ..:.||..:|.|||.||:|.||..|...:...|.........|......|.|.|:|.||.|..:.
  Fly   379 GGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKV 443

  Fly   436 KEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMR 470
            ...::.:||||||..::.|:||||.:|:...:|::
  Fly   444 ASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQ 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	131/476 (28%)
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	135/489 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445713
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.950