DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and Ugt316A1

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001287111.1	Gene:	Ugt316A1 / 40079	FlyBaseID:	FBgn0036842	Length:	636	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	126/490 - (25%)
Similarity:	223/490 - (45%)	Gaps:	32/490 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ANILGVFPYRIPSPFQMVRPLIKALVER--GHKVTMVTP----ADYPAKIDGVRHIRVPMLNQLM 84
            ||:|.|||....|.:...|.|::.|||.  .|.||:::|    ....|:|..:|.:|:   ..|.
  Fly    19 ANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIRELRI---EGLR 80

  Fly    85 QNLMKNDQFFDALGDKWREGVLVSTIFYNVSHAI-LNNNGVQMLMRDKSIR--------FDMIMV 140
            :|.:.....|:|      |.:...::....:..| .....|.:|:.|..:|        ||:::|
  Fly    81 ENWLDMGMSFEA------EEMRAQSVMERFTRLIYAGTTNVDILLSDPQVRKLLTSGEKFDLLIV 139

  Fly   141 EASHLDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPISPNGFALDNTFLSRWSNWI 205
            :....|||.|||.:|....:.:|.......::.:.||...|..:|.:...|........|..|.:
  Fly   140 DLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSL 204

  Fly   206 YITEEKLLERLVFRPAQVRLFKKFFGYPAEKLD---ELRARFSVILVNSHFSMGRVRANVPNIIE 267
            ..|.|:|........:|..::...|....::|.   :|....|:.|:|||..:...||.:||::|
  Fly   205 MSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVE 269

  Fly   268 VAGVHLSE-PPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQ---RV 328
            |.|:|||. ..:.....|..:::.|..|.||||:|.|:....||:.....:|.||..:|:   .:
  Fly   270 VGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLL 334

  Fly   329 IW-KSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQ 392
            .| |.|.:......||:.:.|..||:.:|.||.:::||:..|..||.|:|....|:|.:|:..:|
  Fly   335 KWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQ 399

  Fly   393 FNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWT 457
            .....|:|..|::..:..:.|..|:|:..|::|..|.||.::..::......|..:|:..|:...
  Fly   400 EVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKI 464

  Fly   458 EYALRNRDTSHMRLNVEEIPLMRYYRLDSILTFGV 492
            :..|.:.....::.:...:...|...:|.:|...|
  Fly   465 QLILESGGADFLKSHANTLNFWRAEGVDVLLIIAV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	122/460 (27%)
Ugt316A1	NP_001287111.1	egt	1..480	CDD:223071	122/469 (26%)
Ugt316A1	NP_001287111.1	MGT	39..448	CDD:273616	110/417 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445636
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26285
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860