Protein Alignment Ugt303B2 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 140/554 - (25%)
• Similarity: 241/554 - (43%)
• Gaps: 105/554 - (18%)

  Fly     4 GYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTP------ 62
            |:.....|||| |...|...:...:| |||.. .|.:..:|.:::.|..|||:..::.|
  Rat     5 GFLQKLSGLLL-LLCALPWAEGGKVL-VFPME-GSHWLSMRDVVRELHARGHQAVVLAPEVTVHI 66

  Fly    63 --------ADYPAKI--DGVRHIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYNVSHA 117
                    ..||...  :..||   .:|..| ||..:.:.....:..:......|||.:......
  Rat    67 KEEDFFTLQTYPVPYTKEEYRH---HLLGHL-QNFFETEFSLKLVLQRMAAVNNVSTFYVRSCRG 127

  Fly   118 ILNNNGVQMLMRDKSIRFDMIMVE----ASHLDALY--GLAEFYNATLLGISCMHMTWHIDYLAG 176
            :|:|..:...:...|  ||:::.:    ...:.|:|  ..|.|:..::|   |     .:::.|.
  Rat   128 LLHNTALIQSLNSSS--FDVVLTDPFFPCGAVLAMYLRVPAVFFLQSML---C-----ELEFEAT 182

  Fly   177 NLA-PSVYEP--ISPNGFALDNTFLSRWSN------WIYITE----------EKLLERLV----- 217
            |.. ||.|.|  ::.|...:  :||.|..|      |:|:..          ..||:|.|
  Rat   183 NSPNPSSYIPRLLTLNSDHM--SFLDRVKNMLYPVPWMYLCHVNYGSLARLASDLLQREVSVVEI 245

  Fly   218 FRPAQVRLFKK--FFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPC 280
            .|.|.|.|.:|  .|.||                         |..:||::.:.|::.:. .:|.
  Rat   246 LRHASVWLLRKDFVFYYP-------------------------RPFMPNMVFIGGINCAN-RKPL 284

  Fly   281 GAELQKYLD-EAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENI 344
            ..|.:.|:: ..|||.:.||:|.  ::..:||....::.....::.|.|:|:...:..:|.::|.
  Rat   285 SQEFEAYVNASGEHGIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNT 347

  Fly   345 YVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLD 409
            .::..:||..:|.||..|.||||.|...:.|.|.|||||:.:|||.||.:|..|::..|....|:
  Rat   348 ILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLN 412

  Fly   410 PNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVE 474
            ..::.||.|...:|.::.|.||.:....:::..:|||:.|||.|::|.||.:|::...|:|....
  Rat   413 VLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAH 477

  Fly   475 EIPLMRYYRLDSI---------LTFGVRLGCVCG 499
            ::...:|:.||.|         :.|.|...|..|
  Rat   478 DLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYG 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	Glycosyltransferase_GTB-type	24..464	CDD:471961	123/488 (25%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	133/532 (25%)